Results 1 to 10 of about 321,879 (314)
Inclisiran, Low-Density Lipoprotein Cholesterol and Lipoprotein (a)
Pharmaceuticals, 2023 Dyslipidemia treatment is of major importance in reducing the risk of atherosclerotic cardiovascular disease (ASCVD), which is still the most common cause of death worldwide. During the last decade, a novel lipid-lowering drug category has emerged, i.e.,
Niki Katsiki +3 more
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Low-density lipoprotein particles in atherosclerosis
Frontiers in Physiology, 2022 Among the diseases causing human death, cardiovascular disease (CVD) remains number one according to the World Health Organization report in 2021. It is known that atherosclerosis is the pathological basis of CVD.
Ya-Nan Qiao, Yan-Li Zou, Shou-Dong Guo
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Receptor-mediated low density lipoprotein catabolism in man.
Journal of Lipid Research, 1979 Binding of human low density lipoproteins (LDL) to their specific receptor on cultured cells can be inhibited by treatment with 1,2-cyclohexanedione which blocks a number of functionally significant arginyl residues on the apolipoprotein.
J Shepherd +3 more
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Alternations of Lipoprotein Profiles in the Plasma as Biomarkers of Huntington’s Disease
Cells, 2023 Alterations in lipid composition and disturbed lipoprotein metabolism are involved in the pathomechanism of Huntington’s disease (HD). Here, we measured 112 lipoprotein subfractions and components in the plasma of 20 normal controls, 24 symptomatic ...
Kuo-Hsuan Chang +5 more
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The effect of eight weeks of 30-20-10 interval training on serum spexin levels and lipid profile in obese middle-aged men [PDF]
فیزیولوژی ورزش و فعالیت بدنی, 2023 Background and Purpose: The purpose of this study was to investigate the effect of 30-20-10 interval training on the serum spexin level and lipid profile of obese men in order to measure the effect of physical activity on increasing spexin and improving ...
Hamid Yazdanshenas +2 more
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Biomedicines, 2022 Background: Mechanisms by which chronic kidney disease (CKD) influences fibrin clot properties in atrial fibrillation (AF) remain ill-defined. We aimed to investigate the effects of AF and CKD on fibrin clot properties and lipoproteins, and determine the
Wern Yew Ding +3 more
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The inconspicuous health benefit of blood donation
Global Journal of Transfusion Medicine, 2020 Background and Objectives: Regular blood donations seem to be beneficial to the health of donors in many ways. There is evidence to suggest that blood donation lowers blood viscosity and alters lipid profile, which is an acceptable parameter for ...
Alhaji Bukar +11 more
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Lipids and Lipoproteins in Health and Disease: Focus on Targeting Atherosclerosis
Biomedicines, 2021 Despite advances in pharmacotherapy, intervention devices and techniques, residual cardiovascular risks still cause a large burden on public health. Whilst most guidelines encourage achieving target levels of specific lipids and lipoproteins to reduce ...
Chih-Kuo Lee +5 more
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Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021 Background We have shown previously that low‐density lipoprotein (LDL) can be oxidized in the lysosomes of macrophages, that this oxidation can be inhibited by cysteamine, an antioxidant that accumulates in lysosomes, and that this drug decreases ...
Feroz Ahmad +8 more
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Atorvastatin increases human serum levels of proprotein convertase subtilisin/kexin type 9
Journal of Lipid Research, 2008 Proprotein convertase subtilisin/kexin type 9 (PCSK9) has gained attention as a key regulator of serum low density lipoprotein cholesterol (LDL-C) levels. This novel protease causes the degradation of hepatic low density lipoprotein receptors. In humans,
Holly E. Careskey +5 more
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