Results 31 to 40 of about 585,514 (301)

Cholesteryl ester transfer protein decreases high-density lipoprotein and severely aggravates atherosclerosis in APOE*3-Leiden mice [PDF]

, 2006
OBJECTIVE - The role of cholesteryl ester transfer protein (CETP) in the development of atherosclerosis is still undergoing debate. Therefore, we evaluated the effect of human CETP expression on atherosclerosis in APOE*3-Leiden (E3L) mice with a ...
Dallinga-Thie, G.M. (Geesje), Haan, W. (Willeke) de, Havekes, L.M. (Louis), Hoogt, C.C. (Caroline) van der, Jukema, J.W. (Jan Wouter), Offerman, E. (Erik), Rensen, P.C.N. (Patrick), Westerterp, M. (Marit)   +7 more
core   +5 more sources

Beyond HDL-cholesterol increase: phospholipid enrichment and shift from HDL3 to HDL2 in alcohol consumers

Journal of Lipid Research, 2007
The reduction of cardiovascular mortality associated with moderate alcohol consumption is chiefly thought to be mediated by an increase of high density lipoprotein cholesterol (HDL-CH).
Christian Schäfer, Alexandr Parlesak, Joachim Eckoldt, Christiane Bode, Johann Christian Bode, Winfried März, Karl Winkler   +6 more
doaj   +1 more source

Prevention of low density lipoprotein aggregation by high density lipoprotein or apolipoprotein A-I.

Journal of Lipid Research, 1990
We have shown previously that low density lipoprotein (LDL) subjected to vortexing forms self-aggregates that are avidly phagocytosed by macrophages. That phagocytic uptake is mediated by the LDL receptor.
JC Khoo, E Miller, P McLoughlin, D Steinberg   +3 more
doaj   +1 more source

LDL and HDL transfer rates across peripheral microvascular endothelium agree with those predicted for passive ultrafiltration in humans

Journal of Lipid Research, 2015
The mechanisms by which LDLs and HDLs cross the vascular endothelium from plasma into interstitial fluid are not understood, and have never been studied in humans in vivo.
C. Charles Michel, M. Nazeem Nanjee, Waldemar L. Olszewski, Norman E. Miller   +3 more
doaj   +1 more source

Effect of a novel nutraceutical combination on serum lipoprotein functional profile and circulating PCSK9 [PDF]

, 2017
BACKGROUND: A beneficial effect on cardiovascular risk may be obtained by improving lipid-related serum lipoprotein functions such as high-density lipoproteins (HDLs) cholesterol efflux capacity (CEC) and serum cholesterol loading capacity (CLC) and by ...
Adorni, Maria Pia, Bernini, Franco, Ferri, Nicola, Izzo, Raffaele, Marchiano, Silvia, Rozza, Francesco, Trimarco, Valentina, Zimetti, Francesca   +7 more
core   +3 more sources

Metabolic heterogeneity in the formation of low density lipoprotein from very low density lipoprotein in the rat: evidence for the independent production of a low density lipoprotein subfraction.

Journal of Lipid Research, 1978
The formation of low density lipoprotein (LDL) from very low density lipoprotein (VLDL) was studied after injecting 14C-radiomethylated or 125I-radioiodinated VLDL into rats.
N H Fidge, P Poulis
doaj   +1 more source

Coronary artery endothelial dysfunction is positively correlated with low density lipoprotein and inversely correlated with high density lipoprotein subclass particles measured by nuclear magnetic resonance spectroscopy. [PDF]

, 2009
OBJECTIVE: The association between cholesterol and endothelial dysfunction remains controversial. We tested the hypothesis that lipoprotein subclasses are associated with coronary endothelial dysfunction.
Abhiram Prasad, Amir Lerman, Anderson, Barter, Blake, Bonetti, Cannon, Chait, Charanjit S. Rihal, Colhoun, Cromwell, Deanfield, El Harchaoui, Ford, Forrest, Gurpreet S. Sandhu, Hartman, Hermann, Jeyarajah, Johansson, Joseph P. McConnell, Kathiresan, Kuller, Kuller, Lavi, Lavi, Lerman, Lilach O. Lerman, Mackey, Mackey, Monique A. Ford, Mora, Mora, Otvos, Rosenson, Shahar Lavi, Sirtori, Stacy J. Hartman, Suwaidi, Vakkilainen, van der Steeg, Vergeer, Woodman   +42 more
core   +1 more source

Differential Effects of Lipid-lowering Drugs in Modulating Morphology of Cholesterol Particles. [PDF]

, 2017
Treatment of dyslipidemia patients with lipid-lowering drugs leads to a significant reduction in low-density lipoproteins (LDL) level and a low to moderate level of increase in high-density lipoprotein (HDL) cholesterol in plasma.
Alderete, Benjamin, Amento, Edward P, Kong, Raymond, Liu, David, Lundry, Jason, Madasamy, Shanmugavel, Robinson, J Paul, Wu, Alan HB   +7 more
core   +1 more source

Effects of Diet Composition and Insulin Resistance Status on Plasma Lipid Levels in a Weight Loss Intervention in Women. [PDF]

, 2016
BackgroundOptimal macronutrient distribution of weight loss diets has not been established. The distribution of energy from carbohydrate and fat has been observed to promote differential plasma lipid responses in previous weight loss studies, and insulin
Flatt, Shirley W, Heath, Dennis D, Le, Tran, Natarajan, Loki, Pakiz, Bilge, Quintana, Elizabeth L, Rana, Brinda K, Rock, Cheryl L   +7 more
core   +3 more sources

Intracellular trafficking of pigeon β-very low density lipoprotein and low density lipoprotein at low and high concentrations in pigeon macrophages

Journal of Lipid Research, 2000
Foam cell formation occurs in vitro at lipoprotein concentrations above 50 μg/ml in pigeon macrophages. Hypothetically, intracellular trafficking of lipoproteins at higher concentrations may differ from uptake of lipoproteins associated with low ...
Nancy L. Jones, Jerry A. Saunders, Revill R. Mallory   +2 more
doaj   +1 more source