Results 41 to 50 of about 10,975,472 (295)

Uptake of synthetic low density lipoprotein by leukemic stem cells — a potential stem cell targeted drug delivery strategy [PDF]

, 2010
Chronic Myeloid Leukemia (CML) stem/progenitor cells, which over-express Bcr-Abl, respond to imatinib by a reversible block in proliferation without significant apoptosis.
Jørgensen, Heather G., Jorgensen, Heather G., Tessa L. Holyoake, Heather G. Jørgensen, Elliott, Moira A., Scobie, Linda, Crossan, Claire, Hatziieremia, Sophia, Zhou, Peixun; id_orcid, Elliott, Moira A, Sophia Hatziieremia, Michie, Alison M, Holyoake, Tessa L., Holyoake, Tessa L, Jørgensen, Heather G, Alison M. Michie, Halbert, Gavin W., Linda Scobie, Gavin W. Halbert, Moira A. Elliott, Claire Crossan, Michie, Alison M., Peixun Zhou, Halbert, Gavin W, Zhou, Peixun   +24 more
core   +1 more source

Metabolic heterogeneity in the formation of low density lipoprotein from very low density lipoprotein in the rat: evidence for the independent production of a low density lipoprotein subfraction.

Journal of Lipid Research, 1978
The formation of low density lipoprotein (LDL) from very low density lipoprotein (VLDL) was studied after injecting 14C-radiomethylated or 125I-radioiodinated VLDL into rats.
N H Fidge, P Poulis
doaj   +1 more source

Emerging Risk Markers; Nitric Oxide and Oxidized Low-Density Lipoprotein in Predicting Coronary Heart Disease in Young subjects

International Journal of Research in Pharmaceutical Sciences, 2021
NO is a free radical gas, identified as Endothelial Derived Releasing Factor (EDRF) and synthesized from L-arginine which plays a dynamic role in defence against onset and development of coronary heart disease.
Thirunavukkarasu Jaishankar, Meera Shivasekar, Vinodhini V M   +2 more
doaj   +1 more source

Changes in the Plasma Lipid Profile as a Potential Predictor of Clinical Outcome in Dengue Hemorrhagic Fever [PDF]

, 2002
In 50 consecutive children admitted to the intensive care unit with the clinical diagnosis of dengue hemorrhagic fever (DHF)/dengue shock syndrome (grade III or IV), 20 patients with mild DHF (grade I or II), and 20 healthy control patients, the plasma ...
Suharti, C., Gorp, E. van, van der Meer, Jos W. M., Dolmans, Wil M. V., Meer, J.W.M. van der, Mairuhu, A.T., van der Ven-Jongekrijg, Johanna, Ven-Jongekrijg, J. van der, Demacker, P.N.M., Dolmans, W.M.V., Mairuhu, A.T.A., Mairuhu, ATA, Ven, J. van der, Suharti, Catharina, van Gorp, Eric C. M., Demacker, Pierre N M, Gorp, E.C.M. van   +16 more
core   +1 more source

The metabolic inter-relationships between changes in waist circumference, triglycerides, insulin sensitivity and small, dense low-density lipoprotein particles with acute weight loss in clinically obese children and adolescents. [PDF]

, 2014
OBJECTIVE: Small, dense low-density lipoprotein (LDL) particles are highly atherogenic and strongly associated with obesity-related dyslipidemia. The metabolic inter-relationships between weight loss induced changes in waist circumference, triglycerides,
N. Harman, Smith, A, King, RF, Pemberton, P., Hobkirk, JP, Gately, P, King, R. F., S. Carroll, Carroll, S, P. Pemberton, Pemberton, P, J. H. Barth, Davies, I, Harman, N, Smith, A., Davies, I., Barth, J. H., Harman, N., Hobkirk, J. P., I. Davies, Barth, JH, J. P. Hobkirk, P. Gately, Carroll, S., Gately, P., R. F. King, A. Smith   +26 more
core   +1 more source

Intracellular trafficking of pigeon β-very low density lipoprotein and low density lipoprotein at low and high concentrations in pigeon macrophages

Journal of Lipid Research, 2000
Foam cell formation occurs in vitro at lipoprotein concentrations above 50 μg/ml in pigeon macrophages. Hypothetically, intracellular trafficking of lipoproteins at higher concentrations may differ from uptake of lipoproteins associated with low ...
Nancy L. Jones, Jerry A. Saunders, Revill R. Mallory   +2 more
doaj   +1 more source

Effect of DFPP on Ferroptosis in Peripheral Blood CD14+ Monocytes of Hyperlipidemic Patients Involving the ACSL4/LPCAT3/ALOX5 Pathway

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Hyperlipidemia is a major risk factor for atherosclerotic cardiovascular disease (ASCVD). Although statins are the cornerstone of lipid‐lowering therapy, their use may be limited in some patients by adverse effects. This study evaluated the possible impact of non‐drug treatment using double‐filtration plasmapheresis (DFPP) on CD14+
Yun Cheng, Lan Li, Qingmei Yang, Meipeng Wu   +3 more
wiley   +1 more source

Relation between insulin resistance and fast-migrating LDL subfraction as characterized by capillary isotachophoresis

Journal of Lipid Research, 2005
The proportion of the electronegative low density lipoprotein [LDL(−)] subfraction, which is atherogenic, is increased in type 2 diabetes but is not reduced by glycemic control.
Bo Zhang, Takuya Kaneshi, Takao Ohta, Keijiro Saku   +3 more
doaj   +1 more source

Coronary artery endothelial dysfunction is positively correlated with low density lipoprotein and inversely correlated with high density lipoprotein subclass particles measured by nuclear magnetic resonance spectroscopy. [PDF]

, 2009
OBJECTIVE: The association between cholesterol and endothelial dysfunction remains controversial. We tested the hypothesis that lipoprotein subclasses are associated with coronary endothelial dysfunction.
Prasad, A, McConnell, JP, Ford, MA, Lavi, S, Sandhu, GS, Rihal, CS, Lerman, LO, Lerman, A, Hartman, SJ   +8 more
core   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source