Results 21 to 30 of about 10,450,606 (297)
Journal of Lipid Research, 2008 Separation of lipoproteins by traditional sequential salt density floatation is a prolonged process (∼72 h) with variable recovery, whereas iodixanol-based, self-generating density gradients provide a rapid (∼4 h) alternative.
Michael S. Yee +6 more
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The inconspicuous health benefit of blood donation
Global Journal of Transfusion Medicine, 2020 Background and Objectives: Regular blood donations seem to be beneficial to the health of donors in many ways. There is evidence to suggest that blood donation lowers blood viscosity and alters lipid profile, which is an acceptable parameter for ...
Alhaji Bukar +11 more
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Metabolic origins and clinical significance of LDL heterogeneity
Journal of Lipid Research, 2002 LDLs in humans comprise multiple distinct subspecies that differ in their metabolic behavior and pathologic roles. Metabolic turnover studies suggest that this heterogeneity results from multiple pathways, including catabolism of different VLDL and IDL ...
Kaspar K. Berneis, Ronald M. Krauss
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Low-density lipoprotein particles in atherosclerosis
Frontiers in Physiology, 2022 Among the diseases causing human death, cardiovascular disease (CVD) remains number one according to the World Health Organization report in 2021. It is known that atherosclerosis is the pathological basis of CVD.
Ya-Nan Qiao, Yan-Li Zou, Shou-Dong Guo
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Journal of Lipid Research, 2015 Perlecan is a major heparan sulfate (HS) proteoglycan in the arterial wall. Previous studies have linked it to atherosclerosis. Perlecan contains a core protein and three HS side chains. Its core protein has five domains (DI–DV) with disparate structures
Yu-Xin Xu +8 more
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Non-oxidative modification of native low-density lipoprotein by oxidized low-density lipoprotein [PDF]
Biochemical Journal, 1996 The oxidative modification of low-density lipoprotein (LDL) has been implicated in the pathogenesis of atherosclerosis, although little is known as yet about the precise mechanism of oxidation in vivo. The studies presented here demonstrate that, in the absence of cells or transition metals, oxidized LDL can modify native LDL through co-incubation in ...
M, Yang, D S, Leake, C A, Rice-Evans
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Journal of Lipid Research, 2007 The reduction of cardiovascular mortality associated with moderate alcohol consumption is chiefly thought to be mediated by an increase of high density lipoprotein cholesterol (HDL-CH).
Christian Schäfer +6 more
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Low density lipoprotein misfolding and amyloidogenesis
The FASEB Journal, 2008 ABSTRACT In early atherogenesis, subendothelial retention of lipidic droplets is associated with an inflammatory response‐to‐injury, culminating in the formation of foam cells and plaque. Low density lipoprotein (LDL) is the main constituent of subendothelial lipidic droplets.
Parasassi, T. +11 more
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Prevention of low density lipoprotein aggregation by high density lipoprotein or apolipoprotein A-I.
Journal of Lipid Research, 1990 We have shown previously that low density lipoprotein (LDL) subjected to vortexing forms self-aggregates that are avidly phagocytosed by macrophages. That phagocytic uptake is mediated by the LDL receptor.
JC Khoo +3 more
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Low-Density Lipoprotein Receptors
, 1991 The origins of the receptor theory are based on the work of Paul Ehrlich (1854–1915) and John Newport Langley (1852–1925) (Parascandola 1981), who were the first to postulate that specific cellular reactions to drugs must be based on so-called receptive substances.
Niendorf, A. +2 more
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