Results 141 to 150 of about 428,091 (309)
Angewandte Chemie, EarlyView.Cyclopropene fatty acids have been made that allow the study of fatty acid uptake in complex mixtures of immune cells with single cell resolution and combined with metabolic and proteomic analysis so that for the first time nutrient uptake can be correlated to the phenotype of single immune cell.
Luuk Reinalda +14 more
wiley +2 more sources
Identification of the nucleotide sequence of the lipoprotein lipase gene as well as its role in the development of hyperlipidemia and pancreatitis in the Miniature Schnauzer [PDF]
, 2005 Lipoprotein Lipase (LPL) is a key enzyme in lipid transport. It catalyses the hydrolysis of the triacylglycerol component of chylomicrons and very low-density lipoproteins (VLDL), providing non-esterified fatty acids for tissue utilization.
Schickel, Ralph
core
Annals of Neurology, EarlyView.Objectives The interleukin (IL)‐1, IL‐6, and C‐reactive protein (CRP) pathway is central to the immune response after intracerebral hemorrhage (ICH). We tested for associations between hematoma and plasma cytokine concentrations and patient outcomes in Minimally Invasive Surgery Plus Rt‐PA for ICH Evacuation Phase III (MISTIE III) participants ...
Adrian R. Parry‐Jones +54 more
wiley +1 more source
Angewandte Chemie, EarlyView.A nanopore composed of transmembrane peptides and a DNA scaffold that assists peptide assembly was constructed. By employing peptides containing the unnatural amino acid 2‐aminoisobutyric acid (Aib), which promotes loose packing between helices, a large‐diameter nanopore was achieved.
Zugui Peng +3 more
wiley +2 more sources
Low high-density lipoprotein cholesterol: current status and future strategies for management
, 2010 Vibhuti Singh1, Rakesh Sharma2, Ajoy Kumar3, Prakash Deedwania41University of South Florida College of Medicine, and Suncoast Cardiovascular Center, St. Petersburg, Florida, USA; 2Heart and Vascular Institute of South Arkansas, University of Arkansas for
Vibhuti Singh +3 more
core
Multimorbidity and Associations with Cognition and Alzheimer's Disease Biomarkers
Annals of Neurology, EarlyView.Objective Multimorbidity, the coexistence of 2 or more chronic conditions, has been linked to cognitive aging and Alzheimer's disease (AD) and AD‐related dementias, yet the mechanisms remain unclear. We aimed to examine the associations of multimorbidity with cognition and biomarkers across multiple mechanistic pathways.
Xiaqing Jiang +45 more
wiley +1 more source
, 2007 Patients with growth hormone deficiency (GHD) have increased cardiovascular risk and may show elevated triglyceride and reduced high density lipoprotein (HDL) cholesterol concentrations, two lipid abnormalities usually accompanied by increased small ...
Berneis, Kaspar +3 more
core +1 more source
Therapeutic Applications of Stimuli‐Based Release and Engineering of Extracellular Vesicles
Advanced NanoBiomed Research, EarlyView.This review summarizes the effects of endogenous and exogenous stimuli, their effects on the natural release of extracellular vesicles, as well as their uptake and release. It also gives an overview of stimuli‐responsive EVs and their therapeutic applications. Extracellular vesicles (EVs), nano‐ to microsized lipid bilayer membrane‐bound particles, are
Gloria Kemunto, Kristen Dellinger
wiley +1 more source
Carbohydrate composition of circulating multiple-modified low-density lipoprotein
, 2016 Emile R Zakiev,1 Igor A Sobenin,1,2 Vasily N Sukhorukov,1 Veronika A Myasoedova,1 Ekaterina A Ivanova,3 Alexander N Orekhov1,4 1Laboratory of Angiopathology, Institute for General Pathology and Pathophysiology, 2Laboratory of Medical Genetics, Russian ...
Sukhorukov VN +5 more
core