Results 51 to 60 of about 2,386 (174)

From platelets to particles: Optimizing extracellular vesicle isolation in a National Blood Centre

Vox Sanguinis, Volume 121, Issue 3, Page 245-253, March 2026.
Abstract Background and Objectives Platelet‐derived extracellular vesicles (PEVs) are submicron, membrane‐bound particles released upon platelet activation, with a recognized role in haemostasis, inflammation and immunoregulation. PEVs remain insufficiently characterized in blood products.
Y. Chintala, A. Waters, F. McGrath, A. Lorusso, C. Wynne, S. Meaney   +5 more
wiley   +1 more source

HELP LDL apheresis reduces plasma pentraxin 3 in familial hypercholesterolemia.

PLoS ONE, 2014
BackgroundPentraxin 3 (PTX3), a key component of the humoral arm of innate immunity, is secreted by vascular cells in response to injury, possibly aiming at tuning arterial activation associated with vascular damage.
Michela Zanetti, Mariagrazia Zenti, Rocco Barazzoni, Federica Zardi, Annamaria Semolic, Michele Giuseppe Messa, Filippo Mearelli, Gianpaolo Russi, Maurizio Fonda, Luca Scarano, Enzo Bonora, Luigi Cattin   +11 more
doaj   +1 more source

Management of Pregnancy in a Patient with Familial Hypercholesterolemia and Previous Myocardial Infarction—Treatment with LDL Apheresis: A Case Report

Reports
Familial hypercholesterolemia, a genetic disorder marked by elevated low-density lipoprotein cholesterol (LDL-C), poses significant risks for premature atherosclerosis and cardiovascular diseases, particularly during pregnancy. One of the safe methods of
Milos Milincic, Jovana Todorovic, Stefan Dugalic, Ivana Novakovic, Maja Macura, Katarina Lalic, Miroslava Gojnic Dugalic   +6 more
doaj   +1 more source

[Selective apheresis of low-density lipoproteins].

Medicina (Kaunas, Lithuania), 2006
The case of rare complicated homozygous hypercholesterolemia treated by a direct adsorption of lipoprotein apheresis procedure is presented in this article. In total eight sessions of direct adsorption of lipoprotein apheresis were performed on 14-year-old patient from June 2004 to January 2005. Blood flow rate was 30-50 ml/min.
Antanas, Griskevicius, Judita, Audzijoniene   +1 more
openaire   +1 more source

Population Pharmacokinetics and Exposure‐Response Modeling for Evinacumab in Children, Adolescents, and Adults With Homozygous Familial Hypercholesterolemia

CPT: Pharmacometrics & Systems Pharmacology
Evinacumab, an angiopoietin‐like 3 (ANGPTL3) inhibitor, significantly reduces low‐density lipoprotein cholesterol (LDL‐C), independent of low‐density lipoprotein receptor, in patients with homozygous familial hypercholesterolemia (HoFH).
Sébastien Bihorel, Robert Dingman, Jeanne Mendell, Yuhuan Wang, Poulabi Banerjee, Robert Pordy, John D. Davis, A. Thomas DiCioccio, Lutz Harnisch   +8 more
doaj   +1 more source

Favorable therapeutic efficacy of low-density lipoprotein apheresis for nephrotic syndrome with impaired renal function. [PDF]

Ther Apher Dial, 2022
Muso E, Sakai S, Ogura Y, Yukawa S, Nishizawa Y, Yorioka N, Saito T, Mune M, Sugiyama S, Iino Y, Hirano T, Hattori M, Watanabe T, Yokoyama H, Sato H, Uchida S, Wada T, Shoji T, Oda H, Mori K, Kimura H, Ito O, Nishiyama A, Maruyama S, Inagi R, Fujimoto S, Tsukamoto T, Suzuki Y, Honda H, Babazono T, Tsuruya K, Yuzawa Y.   +31 more
europepmc   +1 more source

Membranous nephropathy complicated by immune thrombocytopenia treated with low-density lipoprotein apheresis: a case report and literature review. [PDF]

CEN Case Rep, 2022
Nishizawa K, Yamashita T, Ogawa Y, Kobayashi H.   +3 more
europepmc   +1 more source

Is it possible to regress atherosclerotic lesions with long-term treatment with lipoprotein apheresis?

Российский кардиологический журнал
The article presents the up-to-date information on the effect of lipoprotein apheresis (LA) on atherosclerotic lesions. Some studies using modern diagnostic imaging techniques (such as intravascular ultrasound or magnetic resonance imaging) have clearly ...
Ulrich Julius, Sergey Tselmin, V. A. Korneva   +2 more
doaj   +1 more source

Lipoprotein-apheresis reduces circulating microparticles in individuals with familial hypercholesterolemia[S]

Journal of Lipid Research, 2014
Lipoprotein-apheresis (apheresis) removes LDL-cholesterol in patients with severe dyslipidemia. However, reduction is transient, indicating that the long-term cardiovascular benefits of apheresis may not solely be due to LDL removal. Microparticles (MPs)
Katherine D. Connolly, Gareth R. Willis, Dev B.N. Datta, Elizabeth A. Ellins, Kristin Ladell, David A. Price, Irina A. Guschina, D. Aled Rees, Philip E. James   +8 more
doaj   +1 more source

Plenary Abstracts Session & Oral Presentations

HemaSphere, Volume 10, Issue S1, June 2026.
wiley   +1 more source