Results 21 to 30 of about 320,078 (208)

Mathematical model for low density lipoprotein (LDL) endocytosis by hepatocytes [PDF]

, 2008
Individuals with elevated levels of plasma low density lipoprotein (LDL) cholesterol (LDL-C) are considered to be at risk of developing coronary heart disease.
B. O’Malley, J. A. D. Wattis, Panovska, J., Byrne, H.M., Jackson, K.G., H. Blackburn, Wattis, JA, H. M. Byrne, L. Pickersgill, O'Malley, B, Panovska, J, Wattis, J.A.D., Pickersgill, L, Pickersgill, L., Blackburn, H, Byrne, HM, Byrne, Helen, K. G. Jackson, Wattis, JAD, O'Malley, B., Blackburn, H., Jackson, KG, J. Panovska   +22 more
core   +1 more source

Disruption of ldlr causes increased LDL-c and vascular lipid accumulation in a zebrafish model of hypercholesterolemia[S]

Journal of Lipid Research, 2014
Hyperlipidemia and arterial cholesterol accumulation are primary causes of cardiovascular events. Monogenic forms of hyperlipidemia and recent genome-wide association studies indicate that genetics plays an important role.
Elizabeth A. O'Hare, Xiaochun Wang, May E. Montasser, Yen-Pei C. Chang, Braxton D. Mitchell, Norann A. Zaghloul   +5 more
doaj   +1 more source

A retrospective study of lipid profile in SARS-CoV-2 infection

National Journal of Physiology, Pharmacy and Pharmacology, 2023
Background: Coronavirus disease 2019 (COVID-19), a pandemic, infected millions of individuals globally. Several studies have been done on the demographic, clinical, laboratory, and radiological parameters of SARCoV-2 disease.
Syed Imran Ali, Sumera Tasleem, Mohammed Abdul Muqeeth, Ch. B Sai Srinivas, Hajera Rabbani, Farha Tarannum   +5 more
doaj   +1 more source

Relation of hyperlipidemia in serum and loss of high density lipoproteins in urine in the nephrotic syndrome [PDF]

, 1987
The mechanism leading to hyperlipidemia in the nephrotic syndrome is not fully understood but may be related in part to loss of high density lipoproteins in the urine of patients with nephrosis.
Caselmann, Wolfgang H., Kutschera, P., Weisweiler, P., Jüngst, Dieter   +3 more
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Non-high density lipoprotein cholesterol versus low density lipoprotein cholesterol as a discriminating factor for myocardial infarction

BMC Research Notes, 2012
Background Serum total cholesterol (TC) and LDL cholesterol (LDL-C) have been used as major laboratory measures in clinical practice to assess cardiovascular risk in the general population and disease management as well as prognosis in patients. However,
Sigdel Manoj, Yadav Binod, Gyawali Prajwal, Regmi Prashant, Baral Sushil, Regmi Shyam, Jha Bharat   +6 more
doaj   +1 more source

Effects of dalcetrapib in patients with a recent acute coronary syndrome [PDF]

, 2012
In observational analyses, higher levels of high-density lipoprotein (HDL) cholesterol have been associated with a lower risk of coronary heart disease events.
Chaitman Bernard R., Nicholls, Stephen J., Mundl, Hardi,, Ballantyne, Christie M,, Nicholls, Stephen J,, Ballantyne, Christie M., Shah, P.K., Ballantyne Christie M., Ballantyne C.M., Chaitman B.R., Wright, R Scott,, McMurray, J.J.V., McMurray, John J V, Mundl, H., Abt Markus, Shah, Prediman K., Schwartz, G.G., McMurray, John J. V., Leiter, Lawrence A,, Leiter, Lawrence A., Barter, Philip J., DE CATERINA, Raffaele, Tardif, Jean-Claude,, Barter, P.J., Leiter L.A., McMurray, J., Brumm, J., Wright, R Scott, Olsson, A.G., Abt, Markus,, Shah Prediman K., dal OUTCOMES Investigators, Leitersdorf, E., Ballantyne, C.M., Kallend, David,, Brumm, Jochen, Mundl Hardi, Shah, Prediman K,, Holme, Ingar M., McMurray, John J V,, Holme, Ingar M,, Brumm Jochen, McMurray J.J., Kallend, David, Goldner, David, Wright, R., Tardif, J., Chaitman, Bernard R,, Wright R. Scott, Shah, P., Chaitman, Bernard R., Chaitman, B., Kallend David, Nicholls, Stephen J, Schwartz Gregory G., Barter, Philip J,, Leiter Lawrence A., Tardif, Jean-Claude, Barter P.J., Barter, P., Abt, Markus, Schwartz, Gregory G., Leiter, Lawrence A, Holme I.M., Olsson, A., The dal-OUTCOMES Investigators, Tardif Jean Claude, Holme, Ingar M, Leitersdorf, Eran, Wright, R.S., Barter Philip J., Schwartz, Gregory G,, Olsson Anders G., Leiter, L.A., Olsson A.G., Olsson, Anders G., Schwartz, Gregory G, Colquhoun, David, Leiter, L., Nicholls, S.J., Barter, Philip J, Chaitman, Bernard R, Brumm, Jochen,, Leitersdorf E., Nicholls, S., Chaitman, B.R., Holme, I.M., Holme, I., Kallend, D., Brumm J., Mundl, Hardi, Shah, Prediman K, Nicholls Stephen J., Wright, R. Scott, McMurray John J. V., Kallend D., Olsson, Anders,, Ballantyne, C., Holme Ingar M., Olsson, Anders G, Abt M., Schwartz G.G., Leitersdorf Eran, Abt, M., Ballantyne, Christie M, Schwartz, G., Leitersdorf, Eran,, GOLINO, Paolo   +107 more
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MEDI6012: Recombinant Human Lecithin Cholesterol Acyltransferase, High‐Density Lipoprotein, and Low‐Density Lipoprotein Receptor–Mediated Reverse Cholesterol Transport

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021
Background MEDI6012 is recombinant human lecithin cholesterol acyltransferase, the rate‐limiting enzyme in reverse cholesterol transport. Infusions of lecithin cholesterol acyltransferase have the potential to enhance reverse cholesterol transport and ...
Richard T. George, Liron Abuhatzira, Susan M. Stoughton, Sotirios K. Karathanasis, Dewei She, ChaoYu Jin, Nicholas A. P. S. Buss, Rebecca Bakker‐Arkema, Emily L. Ongstad, Michael Koren, Boaz Hirshberg   +10 more
doaj   +1 more source

A U-shaped association between the LDL-cholesterol to HDL-cholesterol ratio and all-cause mortality in elderly hypertensive patients: a prospective cohort study

Lipids in Health and Disease, 2020
Background The low-density lipoprotein cholesterol/high-density lipoprotein- cholesterol (LDL-C/HDL-C) ratio is an excellent predictor of cardiovascular disease (CVD).
Yu Yu, Minghui Li, Xiao Huang, Wei Zhou, Tao Wang, Lingjuan Zhu, Congcong Ding, Yu Tao, Huihui Bao, Xiaoshu Cheng   +9 more
doaj   +1 more source

Low-Density Lipoprotein Cholesterol and the Risk of Dementia With Stroke [PDF]

JAMA, 1999
Next to Alzheimer disease, vascular dementia is the second most common form of dementia in the elderly, yet few specific risk factors have been identified.To investigate the relationship of plasma lipids and lipoproteins to dementia with stroke.Prospective longitudinal community-based study over a 7-year period (1991-1998).A total of 1111 nondemented ...
Moroney, Joan T., Tang, Ming-Xin, Berglund, L, Small, S, Merchant, C, Bell, K, Stern, Yaakov, Mayeux, R   +7 more
openaire   +3 more sources

Peroxisome Proliferator Activated Receptors and Lipoprotein Metabolism [PDF]

, 2008
Plasma lipoproteins are responsible for carrying triglycerides and cholesterol in the blood and ensuring their delivery to target organs. Regulation of lipoprotein metabolism takes place at numerous levels including via changes in gene transcription.
Kersten, A.H., Sander Kersten
core   +1 more source