Results 71 to 80 of about 10,282,391 (249)

Versatile vector tools for efficient protein screening across multiple expression systems

FEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu, Yaqing Liu, Lei Qin, Feng Yu, Qisheng Wang, Yahui Liu   +5 more
wiley   +1 more source

Investigation of Natural Effective Gamma Dose Rates case study: Ardabil Province in Iran [PDF]

Gamma rays pose enough energy to form charged particles and adversely affect human health. Since, the external exposure of human beings to natural environmental gamma radiation normally exceeds that from all man-made sources combined, natural background ...
زیوری, سحر, صادقی, هادی, Sahar Zivari, Soheila Rahimzadeh, حضرتی, صادق, رحیم زاده, سهیلا, Manouchehr Barak, Abbas Baghi, Hadi Sadeghi, براک, منوچهر, Sadegh Hazrati, نقی زاده باقی, عباس   +11 more
core   +1 more source

Effect of terahertz irradiation on DNA damage repair in living cells

FEBS Open Bio, EarlyView.
We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno, Shota Yamazaki, Hiromichi Hoshina, Masahiko Harata   +3 more
wiley   +1 more source

The impact of long-term low-dose ionizing radiation on human health: risks and protective measures

Frontiers in Medicine
PurposeWith the widespread application of ionizing radiation in medicine and other fields, the health impacts of long-term occupational exposure to low-dose ionizing radiation (LDIR) on the human body have garnered growing attention.
Yue Zhang, Rongrong Li, Xiaoling Li, Ru Li, Tiankun Lu, Xiaohu Zhong, Zexuan Li, Haifang Zhang, Junfeng Wang   +8 more
doaj   +1 more source

In Vivo Mutagenic Effect of Very Low Dose Radiation

Dose-Response, 2006
Almost all of our knowledge about the mutational effect of radiation has come from high dose studies which are generally not relevant to public exposure.
Pamela J. Sykes, Tanya K. Day, Sarah J. Swinburne, Joanne M. Lane, Alexander A. Morley, Antony M. Hooker, Madhava Bhat   +6 more
doaj   +1 more source

Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells

FEBS Open Bio, EarlyView.
Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla, Martín M. Ledesma, Santiago A. Behr, Matías A. Pibuel, María L. Palanek, Daniel H. Grasso, Maria N. Garcia, Juan Garona, Silvina L. Lompardía, Elida Álvarez, Daniela L. Papademetrio   +10 more
wiley   +1 more source

Radiation Effects in CMOS Isolation Oxides: Differences and Similarities With Thermal Oxides [PDF]

, 2013
Radiation effects in thick isolation oxides of modern CMOS technologies are investigated using dedicated test structures designed using two commercial foundries.
Martinez, Martial, Gaillardin, M., Goiffon, Vincent, Gaillardin, Marc, Estribeau, Magali, Paillet, Philippe, Goiffon, V., Girard, Sylvain, Marcandella, Claude, Magnan, Pierre, Martinez, M., Magnan, P.   +11 more
core   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Microdosimetry of diagnostic X-rays: applications of the variance-covariance method. [PDF]

, 1992
Microdosimetric measurements in beams of diagnostic X rays (between 30 and 125 kV) have been performed. In these pulsed radiation fields, microdosimetric measurements are possible only by application of the variance-covariance technique.
Kellerer, Albrecht M., Chen, J., Kellerer, A.M., Roos, H.   +3 more
core   +1 more source

Understanding and Mitigating the Risk of Accelerated Biological Aging in Survivors of Cancer: A Scoping Review

Aging and Cancer, EarlyView.
Cancer treatment is associated with measurable acceleration of biological aging across epigenetic, telomere, senescence, and immune biomarkers. However, biomarker validation and interventional strategies remain limited, especially in hematologic malignancies, underscoring the need for standardized multi‐omic aging assessments and adequately powered ...
Moataz Ellithi, Emily Herdman, Danielle Westmark, Vijaya R. Bhatt   +3 more
wiley   +1 more source