Results 111 to 120 of about 120,684 (195)

Small molecules as arthropod kinin receptor antagonists, feeding modulators, or novel mosquitocidal agents

open access: yesPest Management Science, Volume 82, Issue 7, Page 6842-6863, July 2026.
A two‐pronged screen of small molecules – (1) on recombinant kinin receptor and (2) through topical application – identifies kinin receptor antagonists, feeding behavior modulators, and new mosquitocidal molecules. Abstract BACKGROUND Aedes aegypti and Culex quinquefasciatus mosquitoes are primary vectors for numerous human and animal pathogens and ...
Bianca M. Henriques‐Santos   +1 more
wiley   +1 more source

A low-fat diet supplemented with monounsaturated fat results in less HDL-C lowering than a very-low-fat diet

open access: yes, 1997
Objective. The purpose of this study was to compare the effects of a very-low-fat diet with a low-fat diet supplemented with monounsaturated oil on plasma lipid levels in subjects with hypercholesterolemia. Design.
K O'Dea (10152086)   +2 more
core  

Surgical excision of melanomas in the anal region and reconstruction of the anus in 11 horses

open access: yesEquine Veterinary Education, Volume 38, Issue 7, Page e387-e398, July 2026.
Summary This case report describes the surgical excision of large perianal and perineal melanomas, and reconstruction of the anus in 11 grey horses. Four horses had a history of painful defaecation or urination due to extensive tumours. Seven horses had no clinical signs at the time of admission but had rapidly growing nodules around the anus with ...
F. Somm, A. E. Fürst, M. A. Jackson
wiley   +1 more source

A New Kinetic‐Mechanistic Approach Towards Spectrophotometric Bioanalysis of 2‐Phenylethylamine as a Sympathomimetic Agent Using Sodium Isopropyl Xanthate

open access: yesAnalytical Science Advances, Volume 7, Issue 1, June 2026.
ABSTRACT 2‐Phenylethylamine (2‐PEA), an aromatic biogenic amine, demonstrates significant physiological and toxicological effects on human health. A variety of conventional methods have been widely used for the determination of 2‐PEA. However, the necessity of complex sample preparation and high cost of instrumentation may pose challenges to their ...
Fatemeh Nami   +3 more
wiley   +1 more source

Clinical pharmacology and prescribing education: An updated medical school curriculum from the British Pharmacological Society

open access: yesBritish Journal of Clinical Pharmacology, Volume 92, Issue 6, Page 1787-1808, June 2026.
Aims Prescribing is a complex, essential skill that doctors must acquire to practice medicine safely and effectively. The British Pharmacological Society has historically provided a core curriculum to guide clinical pharmacology and prescribing education in UK medical schools.
Dagan O. Lonsdale   +5 more
wiley   +1 more source

An Investigation of the Health Benefits of Honey as a Replacement For Sugar In the Diet

open access: yes, 2008
Sugar (primarily sucrose) has been a part of the daily diet for literally hundreds of years, but research is now suggesting that sugar intake can be detrimental to our health. In particular, excessive consumption of simple sugars with high glycemic index
Lynne Merran Chepulis   +1 more
core  

Metabolic Fingerprinting of Urine Reveals Metabolite Changes in Women With Breast Cancer

open access: yesCancer Medicine, Volume 15, Issue 6, June 2026.
This study uses metabolomics to compare urine, plasma and serum metabolite profiles across breast cancer, benign breast disease, symptomatic and healthy controls. Significant metabolic differences—especially in amino acids—were found between BC and other groups, with moderate correlations across biofluids, suggesting potential for non‐invasive BC ...
Nur Aimi Aliah Zainurin   +9 more
wiley   +1 more source

Identification of diagnostic biomarkers for neonatal necrotizing enterocolitis via machine learning screening and single‐cell virtual gene knockout validation

open access: yesJournal of Cell Communication and Signaling, Volume 20, Issue 2, June 2026.
Integrated machine learning screening of five gene expression omnibus datasets and 113 algorithm combinations identified three candidate diagnostic biomarkers for neonatal necrotizing enterocolitis: SLC26A3 (downregulated), CCL20, and CXCL5 (both upregulated). Single‐cell RNA sequencing localized CCL20 upregulation predominantly to macrophages.
Xue Liu   +5 more
wiley   +1 more source

Temporal Patterns of Allergen Sensitisation in the General Population: The LEAD Study

open access: yesClinical and Translational Allergy, Volume 16, Issue 6, June 2026.
ABSTRACT Background Allergic sensitisation is traditionally viewed as a stable trait despite studies suggesting that it may vary across life‐course. This study aims to provide longitudinal evidence of allergic sensitisation and its associated factors in the general population.
Charmaine J. M. Lim   +6 more
wiley   +1 more source

Low-Carbohydrate Diet is More Helpful for Weight Loss Than Low-Fat Diet in Adolescents with Overweight and Obesity: A Systematic Review and Meta-Analysis

open access: yes
Yu Zhang,1– 4 Tingting He,1– 4 Yu Hu,1– 4 Chenlin Gao2– 5 1Graduate School, Southwest Medical University, Luzhou, Sichuan, People’s Republic of China; 2Cardiovascular and Metabolic Diseases Key Laboratory of Luzhou, Affiliated Hospital of Southwest ...
He T, Hu Y, Zhang Y, Gao C
core  

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