Results 41 to 50 of about 54,299 (247)

Phase-Shift, Targeted Nanoparticles for Ultrasound Molecular Imaging by Low Intensity Focused Ultrasound Irradiation [Retraction]

International Journal of Nanomedicine, 2022
Li M, Luo H, Zhang W, et al. Int J Nanomedicine. 2018;13:3907–3920. The Editor and Publisher of International Journal of Nanomedicine wish to retract the published article.
Li M, Luo H, Zhang W, He K, Chen Y, Liu J, Chen J, Wang D, Hao L, Ran H, Zheng Y, Wang Z, Li P   +12 more
doaj  

Ultrasound medicine in the era of precision theranostics: Mechanisms, molecular strategies, and clinical translation [PDF]

Iranian Journal of Basic Medical Sciences
Ultrasound (US) has evolved from a solely diagnostic tool into a multifaceted theranostics platform, proficient in both high-resolution imaging and tailored therapeutic intervention.
Lei Wang, Zhiyu Luo, Dan Liu
doaj   +1 more source

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Focused low-intensity pulsed ultrasound upregulates Vimentin protein expression to inhibit chondrocyte apoptosis

陆军军医大学学报, 2023
Objective To investigate the molecular mechanism of focused low-intensity pulsed ultrasound (FLIPUS) to inhibit chondrocyte apoptosis through mechanical effects.
LI Dongqian, YE Haixia, YU Lehua, JIA Lang   +3 more
doaj   +1 more source

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina, Anna Marcé‐Grau, Barbara Masotto, Marta Codina, Lamia BenJemaa, Yasmina Elaribi, Mónica Martinez‐Gallo, Roger Colobran, Angel Sanchez‐Montañez, Irene Valenzuela, Yoshiko Murakami, Alfons Macaya   +11 more
wiley   +1 more source

The Role of Calcitonin Gene‐Related Peptide in High‐Altitude Headache: A Prospective Field Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective High‐altitude headache (HAH) is a common neurological condition associated with rapid ascent to high altitude. The pathophysiological mechanisms underlying HAH remain incompletely understood. Calcitonin gene‐related peptide (CGRP), a neuropeptide implicated in migraine pathophysiology, may play a key role in the pathophysiology of ...
Roman Schniepp, Ludwig Karrasch, Helena Breitenstein, Andreas Straube, Katharina Kamm   +4 more
wiley   +1 more source

Focused low-intensity pulsed ultrasound alleviates osteoarthritis via restoring impaired FUNDC1-mediated mitophagy

iScience, 2023
Summary: Mitophagy is critical for maintaining proper cellular functions, and it contributes to the onset and progression of osteoarthritis (OA). A recent study showed that focused low-intensity pulsed ultrasound (FLIPUS) could activate mitophagy, but ...
Haixia Ye, Dongqian Li, Xia Wei, Lehua Yu, Lang Jia   +4 more
doaj   +1 more source

Neurovascular Contacts in the Pathophysiology of Neuralgic Amyotrophy: An Observational Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neuralgic amyotrophy (NA) is a prevalent, monophasic, multifocal immune‐mediated neuropathy. A distinctive characteristic of the disease is the occurrence of nerve or fascicle constrictions and torsions (NA‐associated focal nerve lesions, NAFL). The pathophysiology underlying this phenomenon remains to be fully elucidated.
Johannes Fabian Holle, Andreas Leha, Volker Limmroth, Wolfram Windisch, Maximilian Zimmermann   +4 more
wiley   +1 more source

A Review of Low-Intensity Transcranial Focused Ultrasound for Clinical Applications [PDF]

Current Behavioral Neuroscience Reports, 2015
The field of therapeutic focused ultrasound neuromodulation has made great advances in the last few years. While no clinical trials of focused ultrasound neuromodulation are yet underway, several human experiments have recently been conducted. There are many potential uses of this new technology, including treatment of numerous psychiatric and ...
A. Bystritsky, A. S. Korb
openaire   +1 more source