Results 31 to 40 of about 54,299 (247)

Effects of Low Intensity Focused Ultrasound on Liposomes Containing Channel proteins [PDF]

Scientific Reports, 2018
AbstractThe ability to reversibly and non-invasively modulate region-specific brain activity in vivo suggests Low Intensity Focused Ultrasound (LIFU) as potential therapeutics for neurological dysfunctions such as epilepsy and Parkinson’s disease. While in vivo studies provide evidence of the bioeffects of LIFU on neuronal activity, they merely hint at
Meghedi Babakhanian, Limin Yang, Bryan Nowroozi, George Saddik, Lilian Boodaghians, Paul Blount, Warren Grundfest   +6 more
openaire   +4 more sources

Low‐Intensity Focused Ultrasound‐Responsive Ferrite‐Encapsulated Nanoparticles for Atherosclerotic Plaque Neovascularization Theranostics

Advanced Science, 2021
Pathological angiogenesis is a crucial factor that causes atherosclerotic plaque rupture. Sinoporphyrin sodium‐mediated sonodynamic therapy (DVDMS‐SDT) induces regression of plaque neovascularization in humans without causing obvious side effects ...
Jianting Yao, Zhuowen Yang, Liandi Huang, Chao Yang, Jianxin Wang, Yang Cao, Lan Hao, Liang Zhang, Jingqi Zhang, Pan Li, Zhigang Wang, Yang Sun, Haitao Ran   +12 more
doaj   +1 more source

Curcumin-Loaded Nanoparticles with Low-Intensity Focused Ultrasound-Induced Phase Transformation as Tumor-Targeted and pH-Sensitive Theranostic Nanoplatform of Ovarian Cancer

Nanoscale Research Letters, 2020
We have developed a simple and versatile nanoplatform using pH-sensitive ferritin nanocages co-loaded with the anticancer drug curcumin (Cur) and liquid fluorocarbon perfluorohexane (PFH) inside the core and conjugated tumor-targeting molecule FA outside
Xiaoxia Guo, Jie Mei, Yong Jing, Shiguang Wang   +3 more
doaj   +1 more source

Autonomic modulation by low-intensity focused ultrasound stimulation of the vagus nerve

Journal of Neural Engineering, 2022
Abstract Objective. Our previous study has shown that low-intensity focused ultrasound stimulation (FUS) of the vagus nerve could modulate blood pressure (BP), but its underlying mechanisms remain unclear. We hypothesized that low-intensity FUS of the vagus nerve would regulate autonomic function and thus BP. Approach.
Ning Ji, Yuanheng Li, Jingjing Wei, Fei Chen, Lisheng Xu, Guanglin Li, Wan-Hua Lin   +6 more
openaire   +2 more sources

Noninvasive Monitoring of Tissue Temperature Changes Induced by Focused Ultrasound Exposure using Sparse Expression of Ultrasonic Radio Frequency Echo Signals

Journal of Medical Signals and Sensors
Background: Noninvasive therapies such as focused ultrasound were developed to be used for cancer therapies, vessel bleeding, and drug delivery. The main purpose of focused ultrasound therapy is to affect regions of interest (ROI) of tissues without any ...
Kiarash Behnam Malekzadeh, Hamid Behnam, Jahangir (Jahan) Tavakkoli   +2 more
doaj   +1 more source

Sonication of the anterior thalamus with MRI-Guided transcranial focused ultrasound (tFUS) alters pain thresholds in healthy adults: A double-blind, sham-controlled study

Brain Stimulation, 2020
Background: Transcranial focused ultrasound (tFUS) is a noninvasive brain stimulation method that may modulate deep brain structures. This study investigates whether sonication of the right anterior thalamus would modulate thermal pain thresholds in ...
Bashar W. Badran, Kevin A. Caulfield, Sasha Stomberg-Firestein, Philipp M. Summers, Logan T. Dowdle, Matt Savoca, Xingbao Li, Christopher W. Austelle, E. Baron Short, Jeffrey J. Borckardt, Norman Spivak, Alexander Bystritsky, Mark S. George   +12 more
doaj   +1 more source

Modulation of EEG Frequency Characteristics by Low-Intensity Focused Ultrasound Stimulation in a Pentylenetetrazol-Induced Epilepsy Model

IEEE Access, 2021
Treatments for epilepsy include pharmacotherapy or surgery. Recently, focused ultrasound stimulation has been investigated as a promising non-invasive neuromodulation tool for neurological disorders, including epilepsy.
Taekyung Kim, Taewoo Kim, Jaesoon Joo, Ikhyun Ryu, Seunghoon Lee, Eunkyoung Park, Young-Min Shon   +6 more
doaj   +1 more source

Potential applications of focused ultrasound for spinal cord diseases: a narrative review of preclinical studies

Brain and Spine
Focused ultrasound (FUS) technology provides unique advantages as a therapy targeting the central nervous system (CNS). We aimed to investigate and summarize the potential applications of FUS in the context of spinal cord diseases. Search strategies were
Ryan Nguyen, Victor Gabriel El-Hajj, Umberto Battistin, Karl J. Habashy, Victor E. Staartjes, Adrian Elmi-Terander, Jingke Zhang, Abdul Karim Ghaith   +7 more
doaj   +1 more source

The Role of Hematopoietic Cell Transplantation in Ataxia‐Telangiectasia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Ataxia‐telangiectasia (A‐T) is a DNA repair disorder characterized by neurodegeneration, immunodeficiency, and cancer predisposition. Hematopoietic cell transplantation (HCT) is an established therapy in related disorders such as Fanconi anemia (FA) and Nijmegen breakage syndrome (NBS), but its role in A‐T is unclear.
Laila Alkhouli, Seth Rotz, Masatoshi Takagi, Richa Sharma   +3 more
wiley   +1 more source

Mechanism by which low-intensity focused ultrasound promotes angiogenesis and neurogenesis after traumatic brain injury in a rat model via the OXA/MAPK signaling pathway

Neural Regeneration Research
Low-intensity focused ultrasound is a type of ultrasound that primarily relies on cavitation and mechanical effects. It is non-invasive, transient, and well tolerated.
Bingkai Ren, Junwei Kang, Peng Yao, Lianghua Huang, Yan Wang, Yang Bai, Zhen Feng   +6 more
doaj   +1 more source