Results 11 to 20 of about 58,071 (211)
Various surgical techniques and pharmaceutical treatments have been developed to improve the current technologies of treating brain diseases. Focused ultrasound (FUS) is a new brain stimulation modality that can exert a therapeutic effect on diseased ...
Hongchae Baek +8 more
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Recent Advances in the Use of Focused Ultrasound as a Treatment for Epilepsy
Epilepsy affects about 1% of the population. Approximately one third of patients with epilepsy are drug-resistant (DRE). Resective surgery is an effective treatment for DRE, yet invasive, and not all DRE patients are suitable resective surgery candidates.
Emma Lescrauwaet +9 more
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Low intensity focused ultrasound: a new prospect for the treatment of Parkinson’s disease
Background: As a chronic and progressive neurodegenerative disease, Parkinson’s disease (PD) still lacks effective and safe targeted drug therapy. Low-intensity focused ultrasound (LIFU), a new method to stimulate the brain and open the blood-brain ...
Yun-Xiao Zhong +5 more
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Therapeutic Ultrasound-Enhanced Immune Checkpoint Inhibitor Therapy
Immune checkpoint inhibitors (ICIs) are designed to reinvigorate antitumor immune responses by interrupting inhibitory signaling pathways and promote the immune-mediated elimination of malignant cells.
Jinyun Yuan +4 more
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Low-Intensity Focused Ultrasound Technique in Glioblastoma Multiforme Treatment
Glioblastoma is one of the central nervous system most aggressive and lethal cancers with poor overall survival rate. Systemic treatment of glioblastoma remains the most challenging aspect due to the low permeability of the blood-brain barrier (BBB) and ...
Rajneesh Mungur +7 more
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Low intensity focused ultrasound (LIFU) has been gaining traction as a non-invasive neuromodulation technology due to its superior spatial specificity relative to transcranial electrical/magnetic stimulation.
John Dell'Italia +9 more
doaj +1 more source
Real time and delayed effects of subcortical low intensity focused ultrasound
Deep brain nuclei are integral components of large-scale circuits mediating important cognitive and sensorimotor functions. However, because they fall outside the domain of conventional non-invasive neuromodulatory techniques, their study has been ...
Joshua A. Cain +7 more
doaj +1 more source
Noninvasive Low-Intensity Focused Ultrasound Mediates Tissue Protection following Ischemic Stroke
Objective and Impact Statement. This study examined the efficacy and safety of pulsed, low-intensity focused ultrasound (LIFU) and determined its ability to provide neuroprotection in a murine permanent middle cerebral artery occlusion (pMCAO) model ...
Alexandra M. Kaloss +6 more
doaj +1 more source
A pilot clinical study of low-intensity transcranial focused ultrasound in Alzheimer’s disease [PDF]
Purpose Increasing attention has been paid to low-intensity transcranial focused ultrasound (tFUS) for its potential therapeutic effects in Alzheimer's disease (AD). While preclinical studies have shown promising therapeutic effects of low-intensity tFUS
Hyeonseok Jeong +7 more
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Pathological angiogenesis is a crucial factor that causes atherosclerotic plaque rupture. Sinoporphyrin sodium‐mediated sonodynamic therapy (DVDMS‐SDT) induces regression of plaque neovascularization in humans without causing obvious side effects ...
Jianting Yao +12 more
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