LOW MOLECULAR WEIGHT HEPARINS [PDF]
Low-molecular-weight heparins (LMWH) are a new group of parenteral anticoagulants. They represent a major clinical advance in anticoagulation since the identification of unfractionated heparin (UFH) in 1922 and the introduction of the synthetic coumarin derivative, warfarin, in 1948.
J N, Huang, A, Shimamura
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Poly(dimethylsiloxane)-poly(ethyleneoxide)-heparin block copolymers. I. Synthesis and characterization [PDF]
Amphiphilic block copolymers containing poly(dimethylsiloxane), poly(ethylene oxide), and heparin (PDMS-PEO-Hep) have been prepared via a series of coupling reactions using functionalized prepolymers, diisocyanates, and derivatized heparins.
Agarwal +40 more
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Low-Molecular Weight Heparin Increases Circulating sFlt-1 Levels and Enhances Urinary Elimination [PDF]
Rationale: Preeclampsia is a devastating medical complication of pregnancy which leads to maternal and fetal morbidity and mortality. While the etiology of preeclampsia is unclear, human and animal studies suggest that excessive circulating levels of ...
Hagmann, Henning +10 more
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Low molecular weight heparins [PDF]
A new class of anticoagulant with advantages over standard heparin were introduced in 1990. Collectively termed low molecular weight heparins, their role is increasing in the treatment and prophylaxis of thromboembolism.
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Present and future of low molecular weight heparin prophylaxis [PDF]
Peer ...
Kakkar, V. V.
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Low molecular-weight heparin is better than warfarin for prevention of recurrent venous thromboembolism in cancer patients [PDF]
A critical appraisal and clinical application of Lee AYY, Levin MN, Bake RI, et al. Low-molecular-weight heparin versus a coumarin for the prevention of recurrent venous thromboembolism in patients with cancer. N Engl J Med. 2003;349:146-153.
Choi, Sarah
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The potential for circular dichroism as an additional facile and sensitive method of monitoring low-molecular-weight heparins and heparinoids [PDF]
The ultraviolet circular dichroism (CD) spectra of commercial low-molecular-weight heparins, heparinoids and other anticoagulant preparations have been recorded between 180 and 260 nm.
Fernig, David G. +7 more
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Efficacy, Safety, and Timing of Anticoagulant Thromboprophylaxis for the Prevention of Venous Thromboembolism in Patients With Acute Spinal Cord Injury: A Systematic Review [PDF]
Study Design: Systematic review. Objectives: The objective of this study was to answer 5 key questions: What is the comparative effectiveness and safety of (1a) anticoagulant thromboprophylaxis compared to no prophylaxis, placebo, or another ...
Arnold, Paul M. +10 more
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Cancer patients’ experiences of living with venous thromboembolism: A systematic review and qualitative thematic synthesis [PDF]
Background: Cancer-Associated thrombosis is common. Recommended treatment is daily injected low-molecular-weight heparin for 6months. Most studies focus on prophylaxis and treatment; few have explored patients’ experience.
Benelhaj, Naima B. +5 more
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Anticoagulants for acute ischaemic stroke [PDF]
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Counsell, Carl +2 more
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