Results 21 to 30 of about 12,776,407 (326)

Intermediate-dose versus low-dose low-molecular-weight heparin in pregnant and post-partum women with a history of venous thromboembolism (Highlow study): an open-label, multicentre, randomised, controlled trial.

The Lancet, 2022
BACKGROUND Pregnancy-related venous thromboembolism is a leading cause of maternal morbidity and mortality, and thromboprophylaxis is indicated in pregnant and post-partum women with a history of venous thromboembolism.
I. Bistervels, A. Buchmüller, H. Wiegers, F. N. Ní Áinle, B. Tardy, J. Donnelly, P. Verhamme, A. F. Jacobsen, A. T. Hansen, M. Rodger, M. Desancho, R. Shmakov, N. van Es, M. Prins, C. Chauleur, S. Middeldorp   +15 more
semanticscholar   +1 more source

Heparin, Low Molecular Weight Heparin, and Non-Anticoagulant Derivatives for the Treatment of Inflammatory Lung Disease

Pharmaceuticals, 2023
Unfractionated heparin has multiple pharmacological activities beyond anticoagulation. These anti-inflammatory, anti-microbial, and mucoactive activities are shared in part by low molecular weight and non-anticoagulant heparin derivatives.
J. Shute
semanticscholar   +1 more source

Low-molecular-weight heparin for prevention of preeclampsia and other placenta-mediated complications: a systematic review and meta-analysis.

American Journal of Obstetrics and Gynecology, 2021
BACKGROUND Evidence on the impact of low-molecular-weight heparin, alone or in combination with low-dose aspirin, for the prevention for preeclampsia in high-risk patients is conflicting.
M. Cruz-Lemini, J. Vázquez, J. Ullmo, E. Llurba   +3 more
semanticscholar   +1 more source

Low molecular weight heparin in COVID-19: benefits and concerns

Frontiers in Pharmacology, 2023
Since its emergence, the COVID-19 pandemic had a dramatic impact on the public health worldwide and it scarred the medical, economical, and social determinants of health.
Adham Makarem, Adham Makarem, Rana Zareef, Joseph Abourjeili, Joseph E Nassar, Fadi Bitar, Fadi Bitar, Fadi Bitar, Mariam Arabi, Mariam Arabi, Mariam Arabi   +10 more
doaj   +1 more source

Microneedle based transcutaneous delivery of low molecular weight heparin

Pakistan Journal of Pharmaceutical Sciences, 2021
This study aimed to fabricate and characterize polymeric microneedle patches for rapid and non-invasive administration of enoxaparin across skin layers. The patches comprising of PVA, sorbitol and enoxaparin sodium were prepared by employing micromolding
Saman Zafar, Sana Hassan, Jahanzeb Mudassir, Amjad Hussain, Nasir Abbas, Sumera Latif, Ejaz Ali, Muhammad Sohail Arshad   +7 more
doaj   +1 more source

The Effect of Low Molecular Weight Heparins on Placentation: A Rat Model Study

Cumhuriyet Science Journal, 2022
Low molecular weight heparins (LMWHs) have been used for the treatment for recurrent pregnancy loss (RPL) for a long time. We aimed to investigate the efficacy of the LMWHs on angiogenesis and apoptosis during placentation.
Gülizar Özer, Çağlar Yıldız, Hatice Özer, Ali Çetin   +3 more
doaj   +1 more source

The Potential of Low Molecular Weight Heparin to Mitigate Cytokine Storm in Severe COVID‐19 Patients: A Retrospective Cohort Study

Clinical and Translational Science, 2020
On March 11, 2020, the World Health Organization declared its assessment of coronavirus disease 2019 (COVID‐19) as a global pandemic. However, specific anti‐severe acute respiratory syndrome‐coronavirus 2 (SARS‐CoV‐2) drugs are still under development ...
Chen Shi, Cong Wang, Han-Xiang Wang, Chao Yang, Fei Cai, F. Zeng, Fang Cheng, Yi-Hui Liu, Tao Zhou, Bin Deng, I. Vlodavsky, Jin-Ping Li, Yu Zhang   +12 more
semanticscholar   +1 more source

Low Molecular Weight Heparin, Anti-inflammatory/Immunoregulatory and Antiviral Effects, a Short Update

Cardiovascular Drugs and Therapy, 2021
Low molecular weight heparin (LMWH) is a glycosaminoglycan long known for its anticoagulant properties. In recent times, recent evidence has associated this drug with extra pleiotropic anticoagulant effects that have also proven useful in the management ...
A. Vitiello, F. Ferrara
semanticscholar   +1 more source

Low molecular weight heparins [PDF]

Intensive and Critical Care Nursing, 1996
A new class of anticoagulant with advantages over standard heparin were introduced in 1990. Collectively termed low molecular weight heparins, their role is increasing in the treatment and prophylaxis of thromboembolism.
openaire   +4 more sources

Heparin-induced thrombocytopenia and acute colonic pseudo-obstruction after therapeutic anticoagulation in a very elderly patient with hip fracture: a case report

BMC Musculoskeletal Disorders, 2020
Background Hip fractures have become a severe public health problem, especially in very elderly patients. Most of them are treated with low molecular weight heparin as prophylaxis or treatment of venous thromboembolism.
Yijun Liu, Hao Lu, Hailin Xu, Zhongguo Fu, Dianying Zhang, Baoguo Jiang   +5 more
doaj   +1 more source