Results 1 to 10 of about 26,122 (117)

The effectiveness of unfractionated heparin vs. low molecular weight (Enoxaparin) in Acute Respiratory Distress Syndrom (ARDS) and metabolic dysfunction: an old drug for new indication! [PDF]

BMC Immunology
Background Acute Respiratory Distress Syndrome is a lung disorder defined by the acute onset of hypoxemia, the commonest being abdominal sepsis.Many biomarkers have been studied for diagnostic prognostication and ARDS pharmacotherapy.
Shabnam Delasoud, Mojtaba Mojtahedzadeh, Mohammad Sharifzadeh, Mohammad Hossein Ghahremani, Abbass Kebriaeezadeh, Maryam Gholami, Samin Sabzevari, Omid Sabzevari   +7 more
doaj   +2 more sources

Comparative Analysis of Anticoagulation Stability in Critically Ill Patients Receiving Argatroban for Suspected or Confirmed Heparin-Induced Thrombocytopenia Compared with Unfractionated Heparin: A Retrospective Cohort Study [PDF]

Hematology Reports
Background: Achieving and maintaining therapeutic anticoagulation with unfractionated heparin in critically ill patients is challenging due to biologic variability, heparin resistance, and limitations of activated partial thromboplastin time (aPTT ...
Imran Khan, Elizabeth Lamarche, Bernadett Kovacs, Ariel Hendin, Andy Pan, Caitlin Richler, Christine Landry, Sydney Morin, Kaouther Derouiche, Pierre Thabet   +9 more
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The Effect of Exercise on Pharmacodynamics and Pharmacokinetics of a Single Dose of Unfractionated Heparin—A Randomized, Controlled, Crossover Study [PDF]

Clinical and Translational Science
Exercise increases blood and lymph flow in working muscles, potentially affecting the bioavailability and effect of subcutaneously administered drugs. The aim of this study was to assess the influence of a single exercise session on pharmacokinetics and ...
Liva K. Stuhr, Joshua B. Feinberg, Thea Christoffersen, Konstantinos Dimopoulos, Mikkel B. Christensen, David P. Sonne, Troels Riis, Peter S. Plomgaard, Jens P. Goetze, Emil L. Larsen, Kristian Karstoft   +10 more
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Protective Effect of Unfractionated Heparin on Lipopolysaccharide-Induced Acute Respiratory Distress Syndrome in Neonatal Mice via the JAK2/STAT3 Signaling Pathway

Frontiers in Bioscience-Landmark, 2023
Background: Neonatal acute respiratory distress syndrome (ARDS) is a clinical disorder characterized by excessive acute inflammatory response in lung parenchyma and has high morbidity and mortality.
Jing Xiong, Qing Ai, Lei Bao, Yuan Shi
doaj   +1 more source

Effectiveness of early heparin therapy on outcomes in critically ill patients with sepsis-induced coagulopathy

Frontiers in Pharmacology, 2023
Background: This study aimed to investigate whether early unfractionated heparin (UFH) administration provides a survival advantage for patients with sepsis-induced coagulopathy (SIC).Methods: Patients hospitalized with sepsis-induced coagulopathy from ...
Jia-Jia Huang, Jia-Jia Huang, Zhi-Ye Zou, Zhi-Peng Zhou, Yan Liu, Zhen-Jia Yang, Zhen-Jia Yang, Jing-Jing Zhang, Jing-Jing Zhang, Ying-Yi Luan, Yong-Ming Yao, Ming Wu, Ming Wu, Ming Wu   +13 more
doaj   +1 more source

The effect of bivalirudin on coagulation function in male patients with coronary heart disease undergoing percutaneous coronary intervention

Pakistan Journal of Pharmaceutical Sciences, 2023
Aim of this study was to explore the effect of bivalirudin on coagulation function with the treatment of percutaneous coronary intervention (PCI) in male coronary heart disease (CHD) patients.
Dequan Jia, Xiaomei Wei, Bo Qin, Jie Huang   +3 more
doaj   +1 more source

Unfractionated heparin displaces sFlt-1 from the placental extracellular matrix

Biology of Sex Differences, 2020
Soluble vascular endothelial growth factor receptor-1 (sFlt-1) is an anti-angiogenic protein which is secreted by numerous cell types and acts as a decoy receptor for the angiogenic protein vascular endothelial growth factor (VEGF).
Kyle H. Moore, Heather Chapman, Eric M. George   +2 more
doaj   +1 more source

Venous Thromboembolism Prophylaxis with Enoxaparin Versus Unfractionated Heparin in Patients with Low Body Weight

Plasmatology, 2023
Background Although reduced doses of enoxaparin have been studied in low body weight patients, no study has directly compared enoxaparin to unfractionated heparin for venous thromboembolism (VTE) prophylaxis in this population. Objective To determine the
David Michael Kaylor PharmD, Regan Merrell Wade PharmD, BCPS, Kathryn Brinkley Chappell PharmD, BCPS, Meredith Huff Niemann PharmD, BCPS, Vanessa Marie VanArsdale PharmD, BCPS   +4 more
doaj   +1 more source

Oral heparin: status review

Thrombosis Journal, 2006
Unfractionated heparin and low molecular weight heparin are the most commonly used antithrombotic and thromboprophylactic agents in hospital practice.
Gomez-Orellana Isabel, Goldberg Michael, Arbit Ehud, Majuru Shingai   +3 more
doaj   +1 more source

Effect of heparin on recurrent IVF-ET failure patients

Asian Pacific Journal of Reproduction, 2023
Objective: To elucidate the possible role of unfractionated heparin in patients with failed repeated in in vitro fertilization and embryo transfer (IVF-ET) and thrombophilia.
Maryam Shirmohamadi, Mehri Mashayekhy, Iraj Alipourfard, Javad Fazeli, Nasrin Ghasemi   +4 more
doaj   +1 more source