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Low-molecular-weight heparin compounds have been used in the treatment of patients with venous thromboembolism for approximately 15 years. Ever since their introduction, there has been discussion about whether low-molecular-weight heparin compounds ...
Harry Büller, M H Prins, Martin H Prins
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The effect of low molecular weight heparin on survival in patients with advanced malignancy.
Journal of Clinical Oncology, 2005PURPOSE Studies in cancer patients with venous thromboembolism suggested that low molecular weight heparin may prolong survival. In a double-blind study, we evaluated the effect of low molecular weight heparin on survival in patients with advanced ...
C. Klerk +10 more
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Heparin and Low-Molecular Weight Heparins in Thrombosis and Beyond
2010Despite efforts in finding and developing new anticoagulants, unfractionated heparin and low molecular weight heparin (LMWH) will continue to play a pivotal role in the management of thrombotic disorders. While bleeding and heparin-induced thrombocytopenia represent major side effects of this drug, it has remained the anticoagulant of choicefor the ...
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Low‐Molecular‐Weight Heparins in Pregnancy
Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, 1999We conducted a systematic review, with MEDLINE and Cochrane Library data base searches and bibliographic reviews, of English‐language reports describing therapy with low‐molecular‐weight heparin (LMWH) in pregnancy. Altogether 40 citations, excluding abstracts, were identified.
M H, Ensom, M D, Stephenson
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Low‐molecular‐weight heparins and angiogenesis
APMIS, 2006The involvement of the vascular system in malignancy encompasses not only angiogenesis, but also systemic hypercoagulability and a pro‐thrombotic state, and there is increasing evidence that pathways of blood coagulation and angiogenesis are reciprocally linked.
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Low molecular weight heparin and atherosclerosis
Current Atherosclerosis Reports, 2004Low molecular weight heparin (LMWH) has dramatically impacted the treatment of venous thromboembolic disease and acute coronary syndromes. Recent studies help define the role of these agents for patients undergoing percutaneous coronary interventions and for patients treated with thrombolytic agents for ST-segment elevation myocardial infarction ...
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