Results 71 to 80 of about 10,778,698 (292)

Low-temperature ventilation pre-heater in combination with conventional room heaters

open access: yes, 2013
The main focus of the present study was to find design requirements for an air-heater that would be able to operate at low pressure loss and low-temperature water supply.
Holmberg, Sture,, Ploskić, Adnan,
core   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

Reduction of the Cavitation Noise in an Automotive Heater Core

open access: yesApplied Sciences
This study investigates the mechanism behind the cavitation-induced noise in an automotive heater core and proposes a structural solution to eliminate it. Abnormal noise during cold-start conditions in a compact passenger vehicle was traced to cavitation
Jeonga Lee   +3 more
doaj   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

open access: yesMolecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim   +11 more
wiley   +1 more source

Thermodynamic irreversibility assessment of a single-cylinder thermal-lag engine through entropy generation analysis

open access: yesApplications in Engineering Science
Thermal-lag engines potentially offer a simple configuration for waste-heat and low-grade heat recovery, but their thermodynamic irreversibilities remain insufficiently characterized. This study presents a numerical investigation of entropy generation in
Duc-Thuan Phung
doaj   +1 more source

Experimental Study on the Performance of Water Source Trans-Critical CO2 Heat Pump Water Heater

open access: yesEnergies, 2017
The effect of the discharge pressure on the performance of the trans-critical CO2 heat pump with a low gas-cooler outlet temperature is experimentally investigated on a test rig of water source heat-pump water heater.
Xiufang Liu   +4 more
doaj   +1 more source

ANALISIS KINERJA HIGH PRESSURE HEATER (HPH) TIPE SHELL AND TUBE HEAT EXCHANGER [PDF]

open access: yes, 2018
Heat exchanger is one of the supporting production equipment that move the heat energy from one of fluid to another fluid flow. One example of a heat exchanger in power plant industry is High Pressure Heater (HPH).
Gahana, Devia
core   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

Heating Performance Enhancement of High Capacity PTC Heater with Modified Louver Fin for Electric Vehicles

open access: yesEnergies, 2019
Electric vehicles use positive temperature coefficient (PTC) heaters and heat pumps to warm the vehicle cabin. High-capacity PTC heaters are needed because heat pump performance decreases sharply in the winter months due to low outdoor temperatures.
Myeong Hyeon Park, Sung Chul Kim
doaj   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

open access: yesFEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana   +5 more
wiley   +1 more source

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