Results 81 to 90 of about 459,286 (299)
Low-Rank Interconnected Adaptation across Layers
Findings of the Association for Computational Linguistics: ACL 2025Accepted to ACL 2025 (findings, long paper)
Zhong, Yibo, Zhao, Jinman, Zhou, Yao
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Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Empirical Evaluation on GPU, Overclocking, and LoRA for Deep Learning on Embedded Systems
IEEE AccessThe use and optimization of deep learning models for embedded systems and mobile devices present real-world challenges, such as limited computational resources, memory size, inference latency, and high-power consumption requirements. This study evaluated
Evandro Raphaloski +2 more
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Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
LoRA Fusion: Enhancing Image Generation
MathematicsRecent advancements in low-rank adaptation (LoRA) have shown its effectiveness in fine-tuning diffusion models for generating images tailored to new downstream tasks.
Dooho Choi, Jeonghyeon Im, Yunsick Sung
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Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
SARA: Singular-Value Based Adaptive Low-Rank Adaption
With the increasing number of parameters in large pre-trained models, LoRA as a parameter-efficient fine-tuning(PEFT) method is widely used for not adding inference overhead. The LoRA method assumes that weight changes during fine-tuning can be approximated by low-rank matrices.
Gu, Jihao +4 more
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The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
A Study on Text Classification in the Age of Large Language Models
Machine Learning and Knowledge ExtractionLarge language models (LLMs) have recently made significant advances, excelling in tasks like question answering, summarization, and machine translation.
Paul Trust, Rosane Minghim
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