Results 151 to 160 of about 323,060 (314)

A Multifunctional Probe for Visualization of the Nanoscale Distribution of Cholesterol in Cells by Expansion Microscopy

Aggregate, EarlyView.
We develop an azido‐ and amino‐functionalized cholesterol probe that can be efficiently fixed and used for expansion microscopy (ExM). This cholesterol probe enables nanoscale tracking of cholesterol distribution dynamics in the endocytic pathway. Combining 10‐fold robust ExM and structured illumination microscopy allows us to resolve cholesterol ...
Gang Wen, Dominic A. Helmerich, Lisa Behringer‐Pließ, Markus Sauer   +3 more
wiley   +1 more source

Metabolic Dysfunction-Associated Steatotic Liver Disease: From a Very Low-Density Lipoprotein Perspective. [PDF]

Biomolecules
Chen Y, Lei K, Liu Y, Liu J, Wei K, Guo J, Su Z.   +6 more
europepmc   +1 more source

Enhanced Multitask Learning with Attention Sparse Routing Mechanism for Intelligent Diabetes Prediction

Advanced Intelligent Systems, EarlyView.
The model leverages patient time‐space information for pattern feature representations. Encoders extract first and second‐order features, aggregated with categorical embeddings and dense features. Task‐specific and shared experts use gated networks, with a dispatch layer routing information for diabetes risk evaluation and blood glucose prediction ...
Yingshuai Wang, Hongpu Hu, Liqin Xie, Qingkun Chen, Xingyun Lei, Panpan Qin, Yan Wang, Xing Gao, Yanli Wan   +8 more
wiley   +1 more source

High-frequency ultrasound induced the preparation of oxidized low density lipoprotein. [PDF]

Ultrason Sonochem
Li Y, Yang W, Zhang X, Ba J, Yang H, Wang W, Zhang K, Yang Z, Liang H, Li Z, Ashokkumar M, Zhang J, Gao Z, Yu Y.   +13 more
europepmc   +1 more source

AI‐Driven Microphysiological Systems for Advancing Nanoparticle Therapeutics

Advanced Intelligent Systems, EarlyView.
This review outlines recent advances in integrating artificial intelligence with microphysiological systems for nanoparticle evaluation. It highlights data‐driven optimization, image‐based prediction, and AI‐enabled analysis frameworks that advance translational research and support the development of personalized nanomedicine. Nanoparticles (NPs) play
Yedam Lee, Jaehong Min, Sujin Kim, Jihoon Ko   +3 more
wiley   +1 more source

Elevated levels of lipoprotein(a) and low-density lipoprotein cholesterol in familial hypercholesterolemia patients: is dual primary prevention already in sight? [PDF]

Front Cardiovasc Med
Vuorio A, Raal FJ, Kovanen PT.
europepmc   +1 more source

Clinlabomics‐Enabled Blending Ensemble Learning for Low‐Cost Pan‐Cancer Detection and Classification Using Routine Clinical Laboratory Data

Advanced Intelligent Systems, EarlyView.
Researchers develop clinlabomics assisted for cancer identification, an artificial intelligence‐powered system using routine clinical lab data to detect and identify 10 cancer types. Tested on 19 199 individuals, it achieves 90.39% sensitivity and 82.41% specificity in cancer detection, with 72.57% accuracy in identifying specific cancer types ...
Bowen Zhang, Lin Li, Long Cheng, Yujie Liu, Zhaoqing Liu, Jiangpeng Wu, Pengyi Zhang, Jiarui Wang, Dekui Zhang, Shuyan Li   +9 more
wiley   +1 more source

Associations of low-density lipoprotein cholesterol and hemoglobin A1C with cardiovascular events and mortality in breast and prostate cancer patients. [PDF]

Int J Cardiol Cardiovasc Risk Prev
Chen YC, Lu JY, Huang CY, Shao YJ.
europepmc   +1 more source

Structure of human plasma low-density lipoproteins: molecular organization of the central core.

, 1977
David Atkinson, R.J. Deckelbaum, Donald Small, G. Graham Shipley   +3 more
openalex   +1 more source

Adverse Cardiovascular Risk Profile and Increased Diurnal Salivary Cortisol in Girls With Turner Syndrome: An Exploratory Study

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Patients with Turner Syndrome (TS) and those exposed to high concentrations of glucocorticoids have a number of characteristics in common, including an increased risk of cardiovascular disease. Pediatric TS patients underwent studies of salivary cortisol (SC) and cortisone (SCn), body composition, continuous glucose monitoring, vascular ...
Lily Jones, Julie Park, Silothabo Dliso, Daniel B. Hawcutt, Alena Shantsila, Gregory Y. H. Lip, Joanne Blair   +6 more
wiley   +1 more source