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Electronegative low-density lipoprotein

Current Opinion in Lipidology, 2004
The occurrence in blood of an electronegatively charged LDL was described in 1988. During the 1990s reports studying electronegative LDL (LDL(-)) were scant and its atherogenic role controversial. Nevertheless, recent reports have provided new evidence on a putative atherogenic role of LDL(-).
Jordi Ordóñez-Llanos   +2 more
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Evaluation of Malondialdehyde Low-Density Lipoprotein Stratified by Low-Density Lipoprotein Cholesterol

Clinical Laboratory, 2017
Malondialdehyde low-density lipoprotein (MDA-LDL) is a major form of oxidized LDL and considered to be more atherogenic than LDL. Information on major determinants of MDA-LDL and their association in subjects who are not under treatment for diabetes mellitus and dyslipidemia is limited.This study included 778 Japanese subjects who were not taking ...
Kengo Moriyama, Eiko Takahashi
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Low-density lipoprotein heterogeneity

Baillière's Clinical Endocrinology and Metabolism, 1995
As a key feature of the ALP, a raised level of small, dense LDL forms part of what is potentially the most common collection of lipoprotein abnormalities to influence the risk of CHD in the general population. The consistency of the association between a prevalence of small, dense LDL and increased risk of CHD is impressive, though the practical ...
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Low Density Lipoproteins and Hypercholesterolemia

1989
Coronary and vascular disease of atherosclerotic origin are the main causes of death and at the same time the most frequent reasons for early invalidity in the Federal Republic of Germany and other industrialized nations. In particular, coronary heart disease (CHD) is the major cause of death in middle-aged men.
H. Funke, G. Assmann, G. Schmitz
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The low density lipoprotein receptor

Biochimica et Biophysica Acta (BBA) - Reviews on Biomembranes, 1989
The study of familial hypercholesterolemia at the molecular level has led to its advancement from a clinical syndrome to a fascinating experimental system. FH was first described 50 years ago by Carl Müller who concluded that the disease produces high plasma cholesterol levels and myocardial infarctions in young people, and is transmitted as an ...
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Modified Low-Density Lipoproteins and High-Density Lipoproteins

Pathophysiology of Haemostasis and Thrombosis, 2006
It has long been known that the oxidative state of the various plasma lipoproteins modulates platelet aggregability, thereby contributing to atherogenesis. Low-density lipoprotein (LDL), occurring in vivo both in the native and oxidised forms, interacts directly with platelets, by binding to specific receptors.
Franz Koller   +3 more
openaire   +2 more sources

Platelet Activation by Low Density Lipoprotein and High Density Lipoprotein

Pathophysiology of Haemostasis and Thrombosis, 2006
Cardiovascular disease is the main cause of death and disability in the Western society. Lipoproteins are important in the development of cardiovascular disease since they change the properties of different cells involved in atherosclerosis and thrombosis. The interaction of platelets with lipoproteins has been under intense investigation. Particularly
Jan-Willem N. Akkerman   +1 more
openaire   +3 more sources

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