Results 21 to 30 of about 605,029 (256)

An integrated mathematical model of cellular cholesterol biosynthesis and lipoprotein metabolism [PDF]

, 2018
Cholesterol regulation is an important aspect of human health. In this work we bring together and extend two recent mathematical models describing cholesterol biosynthesis and lipoprotein endocytosis to create an integrated model of lipoprotein ...
Pool, Frances, Sweby, Peter K., Tindall, Marcus J.   +2 more
core   +2 more sources

High density lipoprotein metabolism in low density lipoprotein receptor-deficient mice1[S]

Journal of Lipid Research, 2014
The LDL receptor (LDLR) and scavenger receptor class B type I (SR-BI) play physiological roles in LDL and HDL metabolism in vivo. In this study, we explored HDL metabolism in LDLR-deficient mice in comparison with WT littermates.
Franz Rinninger, Markus Heine, Roshni Singaraja, Michael Hayden, May Brundert, Rajasekhar Ramakrishnan, Joerg Heeren   +6 more
doaj   +1 more source

Transport of apolipoproteins A-I and A-II by human thoracic duct lymph [PDF]

, 1981
The daily transport of human plasma apolipoproteins A-I and A-II, triglyceride, and total cholesterol from the thoracic duct lymph into plasma was measured in 2 subjects before and 3 subjects after renal transplantation. Lymph triglyceride transport was ~
Anderson, DW, Brewer, HB, Bronzert, TJ, Forte, T, Lindgren, FT, Niblack, GD, Schaefer, EJ, Starzl, TE, Zech, LA   +8 more
core   +1 more source

Disruption of ldlr causes increased LDL-c and vascular lipid accumulation in a zebrafish model of hypercholesterolemia[S]

Journal of Lipid Research, 2014
Hyperlipidemia and arterial cholesterol accumulation are primary causes of cardiovascular events. Monogenic forms of hyperlipidemia and recent genome-wide association studies indicate that genetics plays an important role.
Elizabeth A. O'Hare, Xiaochun Wang, May E. Montasser, Yen-Pei C. Chang, Braxton D. Mitchell, Norann A. Zaghloul   +5 more
doaj   +1 more source

Alterations of intestinal lipoprotein metabolism in diabetes mellitus and metabolic syndrome [PDF]

, 2015
Diabetes and metabolic syndrome are associated with abnormal postprandial lipoprotein metabolism, with a significant delay in the clearance of many lipid parameters, including triglycerides and chylomicrons.
ARCA, Marcello
core   +1 more source

Combined data from LDL composition and size measurement are compatible with a discoid particle shape

Journal of Lipid Research, 2004
The size of LDL is usually reported as particle diameter, with the implicit assumption that it is a spherical particle. On the other hand, data obtained by cryoelectron microscopy and crystallographic analysis suggest that LDL shape may be discoid.
Tom Teerlink, Peter G. Scheffer, Stephan J.L. Bakker, Robert J. Heine   +3 more
doaj   +1 more source

Antibody formation for malignant tumor. II. Antigenicity of Ehrlich ascites tumor lipoprotein [PDF]

, 1970
A unique low density lipoprotein was obtained from the tumor transplanted with a cultured cell line of Ehrlich ascites tumor, JTC-ll cell. The tumor low density lipoprotein electrophoretically migrated as a single band, and the mobility was different ...
Okamura, Shinsuke, Tadatomo, Yasuo, Yamamoto, Yasuhisa   +2 more
core   +1 more source

Coronary artery endothelial dysfunction is positively correlated with low density lipoprotein and inversely correlated with high density lipoprotein subclass particles measured by nuclear magnetic resonance spectroscopy. [PDF]

, 2009
OBJECTIVE: The association between cholesterol and endothelial dysfunction remains controversial. We tested the hypothesis that lipoprotein subclasses are associated with coronary endothelial dysfunction.
Abhiram Prasad, Amir Lerman, Anderson, Barter, Blake, Bonetti, Cannon, Chait, Charanjit S. Rihal, Colhoun, Cromwell, Deanfield, El Harchaoui, Ford, Forrest, Gurpreet S. Sandhu, Hartman, Hermann, Jeyarajah, Johansson, Joseph P. McConnell, Kathiresan, Kuller, Kuller, Lavi, Lavi, Lerman, Lilach O. Lerman, Mackey, Mackey, Monique A. Ford, Mora, Mora, Otvos, Rosenson, Shahar Lavi, Sirtori, Stacy J. Hartman, Suwaidi, Vakkilainen, van der Steeg, Vergeer, Woodman   +42 more
core   +1 more source

1H NMR spectroscopy quantifies visibility of lipoproteins, subclasses, and lipids at varied temperatures and pressures

Journal of Lipid Research, 2019
NMR-based quantification of human lipoprotein (sub)classes is a powerful high-throughput method for medical diagnostics. We evaluated select proton NMR signals of serum lipoproteins for elucidating the physicochemical features and the absolute NMR ...
Daniela Baumstark, Werner Kremer, Alfred Boettcher, Christina Schreier, Paul Sander, Gerd Schmitz, Renate Kirchhoefer, Fritz Huber, Hans Robert Kalbitzer   +8 more
doaj   +1 more source

Effects of Diet Composition and Insulin Resistance Status on Plasma Lipid Levels in a Weight Loss Intervention in Women. [PDF]

, 2016
BackgroundOptimal macronutrient distribution of weight loss diets has not been established. The distribution of energy from carbohydrate and fat has been observed to promote differential plasma lipid responses in previous weight loss studies, and insulin
Flatt, Shirley W, Heath, Dennis D, Le, Tran, Natarajan, Loki, Pakiz, Bilge, Quintana, Elizabeth L, Rana, Brinda K, Rock, Cheryl L   +7 more
core   +3 more sources