Results 51 to 60 of about 605,029 (256)

Effect of a novel nutraceutical combination on serum lipoprotein functional profile and circulating PCSK9 [PDF]

, 2017
BACKGROUND: A beneficial effect on cardiovascular risk may be obtained by improving lipid-related serum lipoprotein functions such as high-density lipoproteins (HDLs) cholesterol efflux capacity (CEC) and serum cholesterol loading capacity (CLC) and by ...
Adorni, Maria Pia, Bernini, Franco, Ferri, Nicola, Izzo, Raffaele, Marchiano, Silvia, Rozza, Francesco, Trimarco, Valentina, Zimetti, Francesca   +7 more
core   +3 more sources

Relation between insulin resistance and fast-migrating LDL subfraction as characterized by capillary isotachophoresis

Journal of Lipid Research, 2005
The proportion of the electronegative low density lipoprotein [LDL(−)] subfraction, which is atherogenic, is increased in type 2 diabetes but is not reduced by glycemic control.
Bo Zhang, Takuya Kaneshi, Takao Ohta, Keijiro Saku   +3 more
doaj   +1 more source

Lipids and Lipoproteins in Health and Disease: Focus on Targeting Atherosclerosis

Biomedicines, 2021
Despite advances in pharmacotherapy, intervention devices and techniques, residual cardiovascular risks still cause a large burden on public health. Whilst most guidelines encourage achieving target levels of specific lipids and lipoproteins to reduce ...
Chih-Kuo Lee, Che-Wei Liao, Shih-Wei Meng, Wei-Kai Wu, Jiun-Yang Chiang, Ming-Shiang Wu   +5 more
doaj   +1 more source

Cholesteryl ester transfer protein decreases high-density lipoprotein and severely aggravates atherosclerosis in APOE*3-Leiden mice [PDF]

, 2006
OBJECTIVE - The role of cholesteryl ester transfer protein (CETP) in the development of atherosclerosis is still undergoing debate. Therefore, we evaluated the effect of human CETP expression on atherosclerosis in APOE*3-Leiden (E3L) mice with a ...
Dallinga-Thie, G.M. (Geesje), Haan, W. (Willeke) de, Havekes, L.M. (Louis), Hoogt, C.C. (Caroline) van der, Jukema, J.W. (Jan Wouter), Offerman, E. (Erik), Rensen, P.C.N. (Patrick), Westerterp, M. (Marit)   +7 more
core   +2 more sources

Differences in the metabolism of oxidatively modified low density lipoprotein and acetylated low density lipoprotein by human endothelial cells: inhibition of cholesterol esterification by oxidatively modified low density lipoprotein.

Journal of Lipid Research, 1989
The rate of degradation of oxidatively modified low density lipoprotein (Ox-LDL) by human endothelial cells was similar to that of unmodified low density lipoprotein (LDL), and was approximately 2-fold greater than the rate of degradation of acetylated ...
I Jialal, A Chait
doaj   +1 more source

Cysteamine Decreases Low‐Density Lipoprotein Oxidation, Causes Regression of Atherosclerosis, and Improves Liver and Muscle Function in Low‐Density Lipoprotein Receptor–Deficient Mice

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021
Background We have shown previously that low‐density lipoprotein (LDL) can be oxidized in the lysosomes of macrophages, that this oxidation can be inhibited by cysteamine, an antioxidant that accumulates in lysosomes, and that this drug decreases ...
Feroz Ahmad, Robert D. Mitchell, Tom Houben, Angela Palo, Tulasi Yadati, Andrew J. Parnell, Ketan Patel, Ronit Shiri‐Sverdlov, David S. Leake   +8 more
doaj   +1 more source

Purification of the apolipoprotein B-67-containing low density lipoprotein particle and its affinity for the low density lipoprotein receptor.

Journal of Lipid Research, 1995
Naturally occurring mutant forms of apolipoprotein B (apoB)-100 may be able to provide valuable information on the structure-function relationships of apoB with the low density lipoprotein (LDL) receptor.
F.K. Welty, L. Seman, F.T. Yen
doaj   +1 more source

The Association Between Cardiovascular Risk and Elevated Triglycerides [PDF]

, 2017
BACKGROUND: The association between elevated triglycerides and cardiovascular risk has been extensively studied. The elevated level of triglycerides occurs through abnormalities in hepatic very low-density lipoprotein (VLDL) production and intestinal ...
Handayani, O. (Olivia), Sargowo, D. (Djanggan)   +1 more
core   +3 more sources

Electronegative LDLs from familial hypercholesterolemic patients are physicochemically heterogeneous but uniformly proapoptotic

Journal of Lipid Research, 2007
A highly electronegative fraction of human plasma LDLs, designated L5, has distinctive biological activity that includes induction of apoptosis in bovine aortic endothelial cells (BAECs).
Hsin-hung Chen, Brian D. Hosken, Max Huang, John W. Gaubatz, Christine L. Myers, Ronald D. Macfarlane, Henry J. Pownall, Chao-yuh Yang   +7 more
doaj   +1 more source

Detection of surface-adsorbed (lipo)proteins by means of a two-step enzyme-immunoassay: a study on the Vroman effect [PDF]

, 1990
In view of reports on the involvement of high-molecular-weight (HMW) kininogen and high-density lipoprotein (HDL) in the Vroman effect, we studied the adsorption of fibrinogen, HMW kininogen, HDL and several other proteins from pooled human plasma and ...
Aken, W.G. van, Bantjes, A., Beugeling, T., Poot, A.   +3 more
core   +2 more sources