Results 81 to 90 of about 323,060 (314)

Charge properties of low density lipoprotein subclasses

open access: yesJournal of Lipid Research, 1997
Measurements of electrophoretic mobility and particle size of low density lipoproteins (LDL) allowed use of standard electrokinetic theory to quantitate LDL charge characteristics from subjects with predominance of large LDL (pattern A, n = 9) or small ...
M La Belle, P J Blanche, R M Krauss
doaj  

Comparison of ten formulae for calculating low-density lipoprotein cholesterol with direct low-density lipoprotein cholesterol measurement

open access: yesCurrent Medicine Research and Practice
Background Accurate lipid profile assessment, mainly low-density lipoprotein cholesterol (LDL-C) measurement, is crucial for diagnosing and managing cardiovascular disease (CVD).
Suriyan S. Nair   +5 more
doaj   +1 more source

Natural Allelic Variations in IbCHYR1–IbZnFR Complex Regulate Fusarium Root Rot Resistance in Sweet Potato

open access: yesAdvanced Science, EarlyView.
FfRlpA2, a conserved Fusarium effector, functions as a protease inhibitor by hijacking the E3 ubiquitin ligase IbCHYR1 to degrade the resistance factor IbZnFR, thereby promoting Fusarium pathogenicity. Conversely, the high dosage Pro::IbZnFRHap2 allele was associated with resistance to root rot disease.
Huan Zhang   +14 more
wiley   +1 more source

Characterization of apoM in normal and genetically modified mice

open access: yesJournal of Lipid Research, 2004
A novel human apolipoprotein [apolipoprotein M (apoM)] was recently described and demonstrated to be a lipocalin. We have now examined apoM in wild-type mice and mice with genetically altered lipoprotein metabolism.
Kirsten Faber   +3 more
doaj  

Pyruvate Carboxylase in Macrophages Aggravates Atherosclerosis by Regulating Metabolism Reprogramming to Promote Inflammatory Responses Through the Hypoxia‐Inducible Factor‐1 Signaling Pathway

open access: yesAdvanced Science, EarlyView.
This study investigates the role of macrophage pyruvate carboxylase (PC) in atherosclerosis (AS) demonstrating that PC upregulation in macrophages promotes metabolism reprogramming to enhance inflammatory responses via the HIF‐1 signaling pathway.
Ling‐Na Zhao   +17 more
wiley   +1 more source

ApoE genotype-specific inhibition of apoptosis

open access: yesJournal of Lipid Research, 2003
Endothelial cell apoptosis can be initiated by withdrawing growth factors or serum, and is inhibited by HDL. Our results show that the total lipoprotein population from apolipoprotein E 4/4 (APOE4/4) sera is less anti-apoptotic than total lipoproteins ...
Robert M. DeKroon   +6 more
doaj  

Integrative Single‐Cell Analysis Reveals Iron Overload‐Induced Senescence and Metabolic Reprogramming in Ovarian Endometriosis‐Associated Infertility

open access: yesAdvanced Science, EarlyView.
Iron overload in ovarian endometriosis (OE) disrupts follicular function and contributes to infertility. This study maps iron‐induced cellular changes using single‐cell and spatial transcriptomics, revealing senescence phenotypes in OE patients and mouse models. Similar patterns are observed in aging ovaries, highlighting iron metabolism as a potential
Yangshuo Li   +14 more
wiley   +1 more source

Serum lipoprotein accumulation in the livers of orotic acid-fed rats

open access: yesJournal of Lipid Research, 1971
This study provides confirmation of previous observations that showed that rats fed a diet containing 1% orotic acid for 7 days develop a fatty liver and that there is an inhibition of the secretion of low density lipoproteins without altering general ...
LAWRENCE A. POTTENGER, GODFREY S. GETZ
doaj  

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