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Low-Grade Gliomas

Current Treatment Options in Oncology, 2009
Low-grade gliomas (LGG) are uncommon central nervous system (CNS) tumors which often present with seizures and few other neurologic signs or symptoms. Multimodality therapy encompassing surgical resection, radiation therapy (RT), and chemotherapy may provide the best disease-free and overall survival (OS).
Jimmy, Ruiz, Glenn J, Lesser
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Low-Grade Lymphoma

Hematology, 2004
AbstractFolicular lymphoma (FL), the second most common subtype of non-Hodgkin lymphoma, shows considerable heterogeneity in its clinical behavior, representative of a biology that appears increasingly complex and diverse. As our knowledge of the molecular basis of FL increases, we strive for an integration between the bench and clinic that yields ...
Jane N, Winter   +2 more
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Low-grade astrocytomas

2010
Glial tumors constitute approximately 50% of newly diagnosed primary brain tumors, with low-grade gliomas (LGG) accounting for approximately 15% of all brain tumors in adults [21]. The subset of tumors classified as LGG represents a heterogeneous group of tumors with astrocytic, oligodendroglial, ependymal, or mixed cellular histologies.
Nader Sanai, Mitchel S Berger
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Low-grade Gliomas

Continuum, 2015
Low-grade gliomas represent one of the most vexing management issues for neuro-oncologists. The relatively long survival compared to other gliomas makes consideration of treatment toxicity, and thus timing of potentially damaging interventions such as surgery, radiation, and chemotherapy, crucial.
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Low grade gliomas

2022
Low grade gliomas concern grade I and grade II tumors. The only grade one tumor is the pilocytic astrocytoma. This is a well-defined tumor with characteristic histology, often accompanied by a cyst. GKNS has been used in surgically inaccessible tumors since 1994.
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Dedifferentiation of Low Grade Chondrosarcomas

Clinical Orthopaedics and Related Research, 1977
In four unusual cases where a low-grade chondrosarcoma suddenly dedifferentiated into a florid, highly-malignant fibrosarcoma, the average survival was 12 months (range 5-18 months). The surgical treatment of chondrosarcoma consists of a primary excisional biopsy, and if dedifferentiation to fibrosarcoma is seen, radical excision and chemotherapy or ...
G B, McFarland, L M, McKinley, R J, Reed
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Pediatric Low-Grade Glioma

2023
Abstract Pediatric low-grade gliomas (PLGGs) are the most common subgroup of central nervous system (CNS) tumors in childhood. These tumors have a good prognosis, especially when they are completely resectable. Traditional cytotoxic chemotherapy and radiation therapy have proved to be effective in many unresectable cases, but careful ...
Sheetal Phadnis, Theodore Nicolaides
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Low-Grade Glioma

2014
Low-grade gliomas are slower growing than their high-grade counterparts. They account for 10-20 % of all primary brain tumors. Median survival is between 4.7 and 9.8 years. The goal of treatment is to prolong overall survival while maintaining good quality of life (QOL). Recent data favors early surgical resection.
Priya, Kumthekar   +2 more
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Low-grade gliomas

2012
Abstract Diffuse infiltrative low-grade gliomas of the cerebral hemispheres in the adult are a group of tumors with distinct clinical, histological, and molecular characteristics, and there are still controversies regarding management. The scientific evidence of papers collected from the literature was evaluated and graded according to European ...
R, Rudà, E, Trevisan, R, Soffietti
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Low-grade gliomas

Current Treatment Options in Oncology, 2001
Low-grade gliomas are uncommon primary brain tumors classified as histologic grades I or II in the World Health Organization (WHO) classification. The most common variants are pilocytic and low-grade astrocytomas, oligodendrogliomas, and mixed oligo-astrocytomas located in the cerebral hemispheres.
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