Results 71 to 80 of about 13,442,946 (252)

21,864 Unresolved, Low-mass Binaries Identified via Their Overluminosity in Gaia Data Release 3 and a Catalog of 347,440 Systems within 100 pc of the Sun

open access: yesThe Astronomical Journal
The fundamental parameters of a low-mass star can potentially be determined from its photometry and astrometry. This is complicated by the fact that 10%–20% of low-mass stars are predicted to be equal-mass binaries.
Zachary Way   +3 more
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Evolution of Low-mass Population III Stars: Convection, Mass Loss, Nucleosynthesis, and Neutrinos

open access: yesThe Astrophysical Journal
The first stars likely formed from pristine clouds, marking a transformative epoch after the dark ages by initiating reionization and synthesising the first heavy elements.
Thiago Ferreira   +3 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Observations of low mass companions to massive stars

open access: yes, 2009
Massive stars are known to be multiple systems, often in tight, short-period OB stars binaries (SB1 and SB2, found by spectroscopic monitoring). However, little is known about low-mass companions to massive stars, such as A, F, and G stars with masses in
H. Zinnecker
core   +1 more source

The UV Legacy Library of Young Stars as Essential Standards (ULLYSES) Large Director’s Discretionary Program with Hubble. I. Goals, Design, and Initial Results

open access: yesThe Astrophysical Journal
Specifically selected to leverage the unique ultraviolet capabilities of the Hubble Space Telescope, the Hubble Ultraviolet Legacy Library of Young Stars as Essential Standards (ULLYSES) is a Director’s Discretionary program of approximately 1000 orbits ...
Julia Roman-Duval   +46 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Discovery of a widely separated binary system of very low mass stars

open access: yes, 2005
We report our discovery of a nearby wide binary system, LP 714-37 AB. Phan-Bao et al. identified LP 714-37 as a mid-M dwarf during a cross-identification of the NLTT and DENIS catalogues.
Phan-Bao, N., Reylé, C., Martín, E. L.
core   +2 more sources

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