Results 71 to 80 of about 38,924 (266)

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

21,864 Unresolved, Low-mass Binaries Identified via Their Overluminosity in Gaia Data Release 3 and a Catalog of 347,440 Systems within 100 pc of the Sun

The Astronomical Journal
The fundamental parameters of a low-mass star can potentially be determined from its photometry and astrometry. This is complicated by the fact that 10%–20% of low-mass stars are predicted to be equal-mass binaries.
Zachary Way, Sébastien Lépine, Jonathan Gagné, Ilija Medan   +3 more
doaj   +1 more source

The average X-ray spectrum of the volume-complete M-, F-, G-, and K-type star sample within 10 pc of the Sun

Astronomy & Astrophysics
Context. The F-, G-, K-, and M-type stars are the most abundant stellar population in the Milky Way and are expected to contribute to its diffuse X-ray emission.
Zheng Xueying, Ponti Gabriele, Locatelli Nicola, Stelzer Beate, Magaudda Enza, Dennerl Konrad, Freyberg Michael J., Sanders Jeremy, Caramazza Marilena, Sasaki Manami, Merloni Andrea, Robrade Jan, Liu Teng, Zhang He-shou, Mayer Martin G. F., Zhang Yi, Yeung Michael C. H., Becker Werner   +17 more
doaj   +1 more source

The Initial Mass Function of Low-mass Stars and Brown Dwarfs in the W3 Complex. [PDF]

Astron J, 2021
Huston MJ, Luhman KL.
europepmc   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Variations in the Milky Way’s Stellar Mass Function at [Fe/H] < −1

The Astrophysical Journal Letters
We present the first determination of the Galactic stellar mass function (MF) for low-mass stars (0.2–0.5 M _⊙ ) at metallicities [Fe/H] ≲ −1. A sample of ∼53,000 stars was selected as metal-poor on the basis of both their halolike orbits and their ...
Jiadong Li, Hans-Walter Rix, Yuan-Sen Ting, Yu-Ting Wang, Szabolcs Mészáros, Ilija Medan, Chao Liu, Zhiqiang Yan, Peter J. Smith, Dan Qiu, Alexandre Roman-Lopes, Gregory M. Green, Danny Horta, Zachary Way, Tadafumi Matsuno, Stefano O. Souza, José G. Fernández-Trincado   +16 more
doaj   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Jsolated Stars of Low Metallicity

Galaxies, 2018
We study the effects of a reduced mass-loss rate on the evolution of low metallicity Jsolated stars, following our earlier classification for angular momentum (J) isolated stars.
Efrat Sabach
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source