Results 91 to 100 of about 25,002,669 (302)

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Growth Rates of Crystal Grains in Snow at Mizuho Station, Antarctica (Special Issue of the Proceedings of the First Symposium on Antarctic Meteorology and Glaciology)

Antarctic Record, 1979
Measurements of the mean cross-sectional area of crystal grams in snow were made with core samples drilled at Mizuho Station, Antarctica. It was found that the cross-sectional area of crystal grains in snow increased with increasing depth till the depth ...
Hideki NARITA, Norikazu MAENO
doaj   +1 more source

Low-temperature heat transfer in nanowires

, 2001
The new regime of low-temperature heat transfer in suspended nanowires is predicted. It takes place when (i) only ``acoustic'' phonon modes of the wire are thermally populated and (ii) phonons are subject to the effective elastic scattering ...
A. Kambili, B. A. Glavin, D. E. Angelescu, D. J. Thouless, J. C. Nabity, K. Schwab, L. D. Landau, L. G. Rego, M. Grimsditch, M. L. Roukes, M. P. Blencowe, N. Nishiguchi, R. Berman, R. Maynard   +13 more
core   +1 more source

Properties of cryogenic and low temperature composite materials – A review

Cryogenics (Guildford), 2020
This paper reviews the literature published since 1994 related to the behaviour of composite materials at low and cryogenic temperatures. The material properties addressed are: tensile, compressive and shear strength, elastic modulus and stress-strain ...
Z. Sápi, R. Butler
semanticscholar   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Yang-Mills thermodynamics at low temperature

, 2007
For the confining phase of SU(2) Yang-Mills thermodynamics we show that the asymptotic series representing the pressure is Borel summable for negative (unphysical) values of a suitably defined coupling constant. The inverse Borel transform is meromorphic
Hofmann, Ralf
core   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Low-temperature antihydrogen-atom scattering

, 2005
A simple method to include the strong force in atom-antiatom scattering is presented. It is based on the strong-force scatteringn length between the nucleon and antinucleon.
Abramowitz, Amoretti, Armour, Batty, Batty, Cohen, Gabrielse, Gabrielse, Jonsell, Jonsell, Jonsell, Jonsell, Kohno, Landau, S. Jonsell, Strasburger, Strasburger, Strasburger, Trueman   +18 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source