Results 81 to 90 of about 25,002,669 (302)

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Electron–phonon coupling in copper intercalated Bi $$_{2}$$ 2 Se $$_{3}$$ 3

open access: yesScientific Reports, 2022
We report charge and heat transport studies in copper-intercalated topological insulator Bi $$_2$$ 2 Se $$_3$$ 3 hybrid devices. Measured conductivity shows impact of quantum corrections, electron–electron and electron–phonon interactions. Our shot noise
Maciej Wiesner   +5 more
doaj   +1 more source

Low Temperature Anomaly in Mesoscopic Kondo Wires [PDF]

open access: yes, 2000
We report the observation of an anomalous magnetoresistance in extremely dilute quasi-one-dimensional AuFe wires at low temperatures, along with a hysteretic background at low fields.
A. C. Hewson   +22 more
core   +4 more sources

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Perspectives on Low-Temperature Electrolysis and Potential for Renewable Hydrogen at Scale.

open access: yesAnnual Review of Chemical and Biomolecular Engineering, 2019
Hydrogen is an important part of any discussion on sustainability and reduction in emissions across major energy sectors. In addition to being a feedstock and process gas for many industrial processes, hydrogen is emerging as a fuel alternative for ...
K. Ayers   +5 more
semanticscholar   +1 more source

Low-temperature paddlewheel effect in glassy solid electrolytes

open access: yesNature Communications, 2020
Glasses are promising electrolytes for use in solid-state batteries. Nevertheless, due to their amorphous structure, the mechanisms that underlie their ionic conductivity remain poorly understood.
Jeffrey G. Smith, Donald J. Siegel
semanticscholar   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Development of high-performance amplifier of ECM-system for ice core analysis and data management

open access: yesAntarctic Record, 1996
An ECM (Electric Conductivity Measurement) apparatus was improved by reconstructing the current meter amplifier. The main improvements were reduction of noise and improvement of reproducibility, and adoption of a floating circuit.
Masayuki Ohi, Hideki Narita
doaj   +1 more source

Properties of Quantum Graphity at Low Temperature

open access: yes, 2011
We present a mapping of dynamical graphs and, in particular, the graphs used in the Quantum Graphity models for emergent geometry, into an Ising hamiltonian on the line graph of a complete graph with a fixed number of vertices.
Caravelli, Francesco   +1 more
core   +1 more source

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