Results 81 to 90 of about 710,341 (267)

Performance of Thermosyphon Rankine Engine as Low Temperature Heat Engine

open access: yes, 2020
Energy harvesting from the low-temperature heat source can be applied from thermosyphon rankine engine (TSR), this devicedepends on rankine cycle where evacuation the pressure from the device will decrease evaporation pressure according to appliedpressure. This engine was developed in little experiments, so a new model was constructed depending on last
openaire   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

A LOW TEMPERATURE DIFFERENCE HEAT ENGINE

open access: yes
This work presents a novel expansion engine operating on a Quasi-Carnot cycle, combining quasi-isothermal and quasi-adiabatic processes. The design integrates thermal energy storage and heat exchange directly within the engine, utilizing alternating hot and cold water sprays to sustain near-isothermal compression and expansion, thereby minimizing ...
openaire   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Josephson weak link based on proximity effect in long bi-metallic thin-film bridge

open access: yesAIP Advances
We prepared a bi-metal Sn/Al thin film bridge of 1 × 5 µm2 in size and exposed it to microwave irradiation in a frequency range of 7 to 40 GHz to explore the Shapiro steps in the current-voltage characteristics, which served as a reliable indicator for ...
O. G. Turutanov   +3 more
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Interferon beta drives therapy resistance in a patient‐derived model of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant   +11 more
wiley   +1 more source

Role of CF4 Addition in Gas-Phase Variations in HF Plasma for Cryogenic Etching: Insights from Plasma Simulation and Experimental Correlation

open access: yesPlasma
The fabrication of semiconductor devices with three-dimensional architectures imposes unprecedented demands on advanced plasma dry etching processes. These include the simultaneous requirements of high throughput, high material selectivity, and precise ...
Shigeyuki Takagi   +4 more
doaj   +1 more source

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

Necessary condition for the existence of a simple closed geodesic on a regular tetrahedron in the spherical space

open access: yesДоповiдi Нацiональної академiї наук України
In the spherical space the curvature of the tetrahedron’s faces equals 1, and the curvature of the whole tetrahedron is concentrated into its vertices and faces. The intrinsic geometry of this tetrahedron depends on the value α of faces angle, where π/3 <
D.D. Sukhorebska
doaj   +1 more source

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