Results 61 to 70 of about 957,129 (290)
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Fiber Metal Laminates under Low Velocity Impact: An Experimental / Analytical Approach [PDF]
Fiber/ metal laminates (FMLs) are hybrid composites consisting of alternating thin layers of metal sheets and fiber reinforced epoxy laminates. In this study, the effect of fiber orientation on impact properties of FML plates is investigated both ...
mostafa sabzikar borojerdi +2 more
doaj +1 more source
Modelling of impact damage and permanent indentation on laminate composite plate [PDF]
This paper deals with impact damage and permanent indentation modelling. A model enabling the formation of damages developing during a low velocity / low energy impact test on laminate composite panels has been elaborated.
Barrau, Jean-Jacques +2 more
core +1 more source
Simulations of dense granular gases without gravity with impact-velocity-dependent restitution coefficient [PDF]
We report two-dimensional simulations of strongly vibrated granular materials without gravity. The coefficient of restitution depends on the impact velocity between particles by taking into account both the viscoelastic and plastic deformations of ...
Andrews +45 more
core +4 more sources
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Fragmentation of ice by low velocity impact [PDF]
Low velocity impact experiments (0.14 to l km/s) carried out in polycrystalline water ice targets at 257 and 81 K resulted in interactions which can be assigned to four fragmentation classes, cratering, erosion, disruption, and total fragmentation ...
Ahrens, Thomas J., Lange, Manfred A.
core
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Regolith behavior under asteroid-level gravity conditions: low-velocity impact experiments
The dusty regolith covering the surfaces of asteroids and planetary satellites differs in size, shape, and composition from terrestrial soil particles and is subject to very different environmental conditions.
Abukhalil, Sumayya +5 more
core +1 more source

