Results 121 to 130 of about 3,701,882 (277)
Zero Lower Bound and negative interest rates: Choices for monetary policy in the UK. [PDF]
J Policy Model, 2021 Nasir MA.
europepmc +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Government Spending, GDP and Exchange Rate in Zero Lower Bound: Measuring Causality at Multiple Horizons. [PDF]
J Quant Econ, 2021 Mao Takongmo CO, Lebihan L.
europepmc +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
A New Approach for Bounding Awards in Bankruptcy Problems
Rect@, 2008 The solution for the Contested Garment Problemproposed in the Babylonic Talmud,one of the most important sources of inspiration for solving situations where demandovercomes supply of some resources, suggests that each agent should receive at least ...
Marco-Gil, M.Carmen +1 more
doaj
Optimal large time behavior of the 3D rate type viscoelastic fluids
Advances in Nonlinear AnalysisWe investigate optimal decay estimates of solutions to the 3D Cauchy problem of the rate type viscoelastic fluids. The main novelty of this article involves three aspects: first, we show that the second-order and third-order spatial derivative of the ...
Chen Yangyang, Zhang Yinghui
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Monotone Projection Lower Bounds from Extended Formulation Lower Bounds
, 2015 Published in Theory of Computing, Volume 13 (2017), Article 18; Received: November 10, 2015, Revised: July 27, 2016, Published: December 22 ...
openaire +2 more sources
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source