Results 91 to 100 of about 1,003,788 (328)
Lower Bounds for the Graph Homomorphism Problem
The graph homomorphism problem (HOM) asks whether the vertices of a given $n$-vertex graph $G$ can be mapped to the vertices of a given $h$-vertex graph $H$ such that each edge of $G$ is mapped to an edge of $H$.
A Björklund +19 more
core +1 more source
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Nonuniform ACC Circuit Lower Bounds [PDF]
The class ACC consists of circuit families with constant depth over unbounded fan-in AND, OR, NOT, and MOD m gates, where m > 1 is an arbitrary constant. We prove the following. ---NEXP, the class of languages accepted in nondeterministic exponential time, does not ...
openaire +2 more sources
Hardness measures and resolution lower bounds [PDF]
Various "hardness" measures have been studied for resolution, providing theoretical insight into the proof complexity of resolution and its fragments, as well as explanations for the hardness of instances in SAT solving.
Beyersdorff, Olaf, Kullmann, Oliver
core
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
The representations, including polynomial, of functions over final fields have been actively investigated. The complexity of such representations is the main stream of research.
A. Baliuk, A.S. Zinchenko
doaj
Some characterizations of error bound for non-lower semicontinuous functions
In this paper, we study the error bound of non-lower semicontinuous functions. First, we extend the concepts of strong slope and global slope to the non-lower semicontinuous functions.
Miantao Chao +2 more
doaj +1 more source
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
We prove a new lower bound for the dilatation of an arbitrary pseudo-Anosov map on a surface of genus g with n punctures. Our bound improves the former super-exponential dependence on the genus by a polynomial dependence.
openaire +5 more sources

