Results 101 to 110 of about 96,047 (264)

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Lower Bounds and Semi On-line Multiprocessor Scheduling [PDF]

open access: yesComputer Science Journal of Moldova, 2003
We are given a set of identical machines and a sequence of jobs from which we know the sum of the job weights in advance. The jobs have to be assigned on-line to one of the machines and the objective is to minimize the makespan.
T.C. Edwin Cheng   +2 more
doaj  

Monotone Circuit Lower Bounds from Robust Sunflowers. [PDF]

open access: yesAlgorithmica, 2022
Cavalar BP, Kumar M, Rossman B.
europepmc   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Erratum to “Lower Bounds for Some Factorable Matrices”

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 2007
The purpose of this erratum is to correct both the mathematical and typographical errors made in 2006.
B. E. Rhoades, Pali Sen
doaj   +1 more source

Monotone Projection Lower Bounds from Extended Formulation Lower Bounds

open access: yesTheory Comput., 2015
Published in Theory of Computing, Volume 13 (2017), Article 18; Received: November 10, 2015, Revised: July 27, 2016, Published: December 22 ...
openaire   +3 more sources

Lower Bounds in Differential Privacy [PDF]

open access: yes, 2012
Corrected some minor errors and typos.
openaire   +2 more sources

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

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