Results 121 to 130 of about 1,003,788 (328)

Lower Bounds of Blow-Up Time for Certain Fractional Diffusion Equations and Systems with Nonlinear Memory Terms in Bounded Domains

Fractal and Fractional
In this paper, we prove the lower bounds of the blow-up time of solutions for certain Caputo time fractional diffusion equations and systems with nonlinear memory terms under homogeneous Dirichlet boundary conditions.
Quanguo Zhang, Yaning Li
doaj   +1 more source

Bayesian Cramér-Rao Lower Bounds for Prediction and Smoothing of Nonlinear TASD Systems. [PDF]

Sensors (Basel), 2022
Li X, Duan Z, Tang Q, Mallick M.
europepmc   +1 more source

Information-Theoretic Lower Bounds for Recovery of Diffusion Network\n Structures [PDF]

, 2016
Keehwan Park, Jean Honorio
openalex   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Lower Bounds for Coulombic Systems. [PDF]

J Chem Theory Comput, 2021
Pollak E, Martinazzo R.
europepmc   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Communication Lower-Bounds for Distributed-Memory Computations for Mass Spectrometry based Omics Data. [PDF]

J Parallel Distrib Comput, 2022
Saeed F, Haseeb M, Iyengar SS.
europepmc   +1 more source

Phase transformations surfaces and exact energy lower bounds [PDF]

, 2015
Mikhail A. Antimonov, Andrej Cherkaev, А. Б. Фрейдин   +2 more
openalex   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Part II: On the Use, the Misuse, and the Very Limited Usefulness of Cronbach's Alpha: Discussing Lower Bounds and Correlated Errors. [PDF]

Psychometrika, 2021
Sijtsma K, Pfadt JM.
europepmc   +1 more source