Results 71 to 80 of about 911,610 (308)
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Did Teachers’ Race and Verbal Ability Matter in the 1960’s? Coleman Revisited [PDF]
, 1993 Our paper reanalyzes data from the classic 1966 study Equality of Educational Opportunity, or Coleman Report. It addresses whether teacher characteristics, including race and verbal ability, influenced synthetic gain scores of students (mean test ...
Brewer, Dominic J, Ehrenberg, Ronald G
core +2 more sources
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
“Educare all'Antico”. Teaching Classical Civilisation in Italian primary and lower secondary schools
The Journal of Classics TeachingThe purpose of this article is to offer an overview of an educational project that brought Classical Civilisation to pupils in the Pisa area between 2004 and 2009, through a cooperation between the Department of Classical Philology at our University and ...
Riccardo Di Donato, Andrea Taddei
doaj +1 more source
Listening comprehension and strategy use: a longitudinal exploration [PDF]
, 2008 This paper examines the development of strategy use over 6 months in two lower-intermediate learners of L2 French in secondary schools in England.
Graham, S. +2 more
core +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Regula falsi in lower secondary school education II
Teaching Mathematics and Computer Science, 2021 The aim of this paper is to investigate the pupils' word problem solving strategies in lower secondary school education. Students prior experiences with solving word problems by arithmetic methods can create serious difficulties in the transition from arithmetic to algebra. The arithmetical methods are mainly based on manipulation with numbers.
openaire +1 more source
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
The Formation of School Peer Groups: Pupils’ Transition from Primary to Secondary School in England [PDF]
This paper examines the transitions from primary to secondary school for a contemporary cohort of children moving between state schools in England. It uses data on over 12,000 primary schools, over 2000 secondary schools and around 400,000 pupils.
Carol Propper +4 more
core
Additional career assistance and educational outcomes for students in lower track secondary schools [PDF]
, 2016 Based on local policy variation, this paper estimates the causal effect of additional career assistance on educational outcomes for students in Lower Track Secondary Schools in Germany.
Fitzenberger, Bernd +1 more
core +2 more sources