Results 61 to 70 of about 8,378 (267)

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Satisfaction and Trust Should First Be Nested in Commitment Before Affecting Loyalty in the Use of Mobile Shopping Applications

open access: yesSAGE Open
This study investigates the active role of commitment in explaining loyalty programs when customers get their satisfaction and trust through a Mobile Shopping Application (MSA).
Sumiyana Sumiyana, Erna Fitri Komariyah
doaj   +1 more source

Green loyalty? Unveiling consumer preferences in sustainable temporary loyalty programs

open access: yesCleaner and Responsible Consumption
Almost every food retailer offers them – temporary loyalty programs (TLPs). TLPs aim to enhance customer loyalty by offering enticing, product-based incentives.
Caspar Krampe   +2 more
doaj   +1 more source

Interferon beta drives therapy resistance in a patient‐derived model of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant   +11 more
wiley   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

open access: yesMolecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas   +16 more
wiley   +1 more source

Determinants of Online Transportation Adoption: An Extended UTAUT2 Model with Loyalty Program

open access: yesJurnal Sistem Informasi
This study investigates the factors influencing the adoption of online transportation services, focusing on loyalty programs within the UTAUT2 framework.
Ivan Dika Lesmana   +2 more
doaj   +1 more source

Satisfaction and loyalty as developing function of customer relationship marketing in terms of globalization [PDF]

open access: yesAnali Ekonomskog fakulteta u Subotici, 2015
Modern companies, in terms of globalization, are confronted with the need to invest significant efforts in order to achieve more efficient and effective use of available marketing resources.
Leković Ksenija, Marić Dražen
doaj  

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

The differences in purchase behavior between redeemers and non-redeemers of coupons at till under retail loyalty programs

open access: yesEkonomski Vjesnik, 2020
Despite the popularity of loyalty programs, evidence on the effects of rewards on consumer behavior is inconsistent. Behavioral loyalty is important for a company as it represents a consumer’s tendency to purchase on a regular basis.
Zrinka Filipović
doaj  

Attracting new customers to loyalty programs: The effectiveness of monetary versus nonmonetary loyalty programs

open access: yesJournal of Consumer Behaviour, 2017
AbstractWhat type of reward attracts customers to loyalty programs? Given the increasing importance of loyalty programs, this question matters. Six sequential studies investigated whether monetary rewards universally attract people more than nonmonetary rewards.
Ruta Ruzeviciute, Bernadette Kamleitner
openaire   +2 more sources

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