Deep coverage whole genome sequences and plasma lipoprotein(a) in individuals of European and African ancestries. [PDF]
, 2018 Lipoprotein(a), Lp(a), is a modified low-density lipoprotein particle that contains apolipoprotein(a), encoded by LPA, and is a highly heritable, causal risk factor for cardiovascular diseases that varies in concentrations across ancestries. Here, we use
Alver, Maris +38 more
core +1 more source
Non-Edg family LPA receptors: the cutting edge of LPA research [PDF]
Journal of Biochemistry, 2011 Lysophosphatidic acid (LPA) is a bioactive lipid mediator with diverse physiological and pathological actions on many types of cells. Originally, LPA was thought to elicit its biological functions through three subtypes of endothelial differentiation gene (Edg) family G protein-coupled receptors (LPA1, LPA2 and LPA3) until our group identified a fourth
Keisuke, Yanagida, Satoshi, Ishii
openaire +2 more sources
Identification of heparin-binding EGF-like growth factor (HB-EGF) as a biomarker for lysophosphatidic acid receptor type 1 (LPA1) activation in human breast and prostate cancers. [PDF]
PLoS ONE, 2014 Lysophosphatidic acid (LPA) is a natural bioactive lipid with growth factor-like functions due to activation of a series of six G protein-coupled receptors (LPA₁₋₆).
Marion David +7 more
doaj +1 more source
Profiling lysophosphatidic acid levels in plasma from head and neck cancer patients [PDF]
PeerJ, 2020 Head and neck squamous cell carcinoma (HNSCC) represents a significant world health problem, with approximately 600,000 new cases being diagnosed annually. The prognosis for patients with HNSCC is poor and, therefore, the identification of biomarkers for
Mariati Abdul Rahman +10 more
doaj +2 more sources
Cross-sectional associations between sleep duration, sedentary time, physical activity, and adiposity indicators among Canadian preschool-aged children using compositional analyses [PDF]
, 2017 Background Sleep duration, sedentary behaviour, and physical activity are three co-dependent behaviours that fall on the movement/non-movement intensity continuum.
AG LeBlanc +42 more
core +4 more sources
Cells, 2022 Systemic inflammation induces alterations in the finely tuned micromilieu of the brain that is continuously monitored by microglia. In the CNS, these changes include increased synthesis of the bioactive lipid lysophosphatidic acid (LPA), a ligand for the
Lisha Joshi +10 more
doaj +1 more source
Antisymmetric and other subleading corrections to scaling in the local potential approximation [PDF]
, 2001 For systems in the universality class of the three-dimensional Ising model we compute the critical exponents in the local potential approximation (LPA), that is, in the framework of the Wegner-Houghton equation.
Bagnuls +30 more
core +4 more sources
European Journal of Psychotraumatology, 2018 Background: The proposed ICD-11 criteria for trauma-related disorders define posttraumatic stress disorder (PTSD) and complex posttraumatic stress disorder (cPTSD) as separate disorders.
Maria Böttche +7 more
doaj +1 more source
Utility of GeneXpert in Diagnosis of Pediatric Tuberculosis and Detection of Rifampicin Resistance [PDF]
Perspectives In Medical ResearchBackground: Tuberculosis (TB) remains a significant public health challenge in developing countries, including India, where children under 15 years account for 12% of all TB cases. The National Tuberculosis Elimination Programme (NTEP) recommends the use
Pooja Shah +6 more
doaj +1 more source
Journal of Inflammation Research, 2023 Ruifeng Bai,1 Jianqiu Pei,1 Shengqiang Pei,1 Xiangfeng Cong,1 Jerold Chun,2 Fang Wang,1,3,4 Xi Chen1,3 1State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and ...
Bai R +6 more
doaj