Results 1 to 10 of about 88,611 (239)
Scientific Reports, 2023 Despite the robust regenerative capacity of the liver, prolonged and severe liver damage impairs liver regeneration, leading to liver failure. Since the liver co-opts the differentiation of liver progenitor cells (LPCs) into hepatocytes to restore ...
Minwook Kim, Juhoon So, Donghun Shin
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Current Research in Pharmacology and Drug Discovery, 2022 Aims: Allergic airway disease manifestation is induced by lysophosphatidylcholine (LPC) through CD1d-restricted Natural killer T (NKT) cells. Choline chloride (ChCl) and LPC both have the “choline” moiety in their structure and this may interplay the ...
Preeti Bansal +4 more
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Lysophosphatidylcholine triggers TLR2- and TLR4-mediated signaling pathways but counteracts LPS-induced NO synthesis in peritoneal macrophages by inhibiting NF-κB translocation and MAPK/ERK phosphorylation. [PDF]
PLoS ONE, 2013 Lysophosphatidylcholine (LPC) is the main phospholipid component of oxidized low-density lipoprotein (oxLDL) and is usually noted as a marker of several human diseases, such as atherosclerosis, cancer and diabetes.
Alan Brito Carneiro +10 more
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Mechanisms involved in the remyelinating effect of sildenafil [PDF]
, 2018 Remyelination occurs in demyelinated lesions in multiple sclerosis (MS) and pharmacological treatments that enhance this process will critically impact the long term functional outcome in the disease.
Díaz-Lucena, Daniela +5 more
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Aquaculture and Fisheries, 2019 An 8-week trial was conducted to investigate graded levels of dietary LPC on growth, apparent digestibility (ADs) of nutrients and lipid metabolism in juvenile turbot Scophthalmus maximus L. Five experimental diets were formulated which contain 11% crude
Baoshan Li +5 more
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Galectin-1 in myelin repair [PDF]
, 2016 Galectin-1 (Gal-1) is a member of a highly conserved family of animal lectins which binds to the common disaccharide [Galβ(1-4)-GlcNAc] on both N- and O-glycans decorating cell surface glycoconjugates.
Pasquini, Laura Andrea +2 more
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Journal of Lipid Research, 2005 Stearoyl lysophosphatidylcholine (LPC) has recently been proven protective against lethal sepsis by stimulating neutrophils to eliminate invading pathogens through an H2O2-dependent mechanism.
Guoqian Chen +11 more
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Cells, 2023 Synovial fluid (SF) from human knee joints with osteoarthritis (OA) has elevated levels of lysophosphatidylcholine (LPC) species, but their functional role is not well understood.
Thomas Timm +5 more
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Frontiers in Molecular Neuroscience, 2022 Lysophosphatidyl-choline (LPC), a member of the phospholipid family, is an emerging player in pain. It is known to modulate different pain-related ion channels, including Acid-Sensing Ion Channel 3 (ASIC3), a cationic channel mainly expressed in ...
Ludivine Pidoux +5 more
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Lysolecithins improved growth performance, nutrient digestibility, immunity, and antioxidant ability in broiler chickens [PDF]
Animal BioscienceObjective This study investigated the effects of dietary supplementation with lysolecithins (LPC) on growth performance, nutrient digestibility, blood profiles, immunity, and liver health in broiler chickens.
Yuanli Cai +3 more
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