Results 1 to 10 of about 6,898 (217)

Phospholipase A2 products influence the antiplatelet functions of synthetic high-density lipoproteins

Journal of Lipid Research
Multiple synthetic high-density lipoproteins (sHDLs) have been developed and extensively evaluated in preclinical and clinical trials, with their functionality potentially linked to specific lipid compositions.
Antonela Rodriguez, Minzhi Yu, Jingyao Gan, May Thazin Phoo, Alankrita Rani, Gunther Marsche, Yanhong Guo, Michael Holinstat, Anna Schwendeman   +8 more
doaj   +1 more source

Effect of adding magnesium salts or different emulsifiers to a fatty acid prill on fatty acid digestibility and milk fat production in lactating dairy cows

Journal of Dairy Science
: Fatty acid (FA) supplements are commonly fed to increase the energy content of lactating dairy cow diets and improve milk and milk fat yield and energy balance. However, increasing dietary fat commonly decreases FA digestibility.
S.L. Burtnett, Y. Adeniji, J. Albrecht, O.R. Drehmel, P. Yoder, M.F. Scott, K.J. Harvatine   +6 more
doaj   +1 more source

Effects of Lysophospholipids on Tumor Microenvironment [PDF]

Cancer Microenvironment, 2011
The effects of lysophospholipids (LPLs) on cancer microenvironment is a vast and growing field. These lipids are secreted physiologically by various cell types. They play highly important roles in the development, activation and regulation of the immune system. They are also secreted by cancerous cells and there is a strong association between LPLs and
Johannes, Rolin, Azzam A, Maghazachi
openaire   +2 more sources

Hydrogen gas with hypothermic machine perfusion induces lipidomic alterations in donation-after-cardiac-death rat livers

Journal of Lipid Research
Hypothermic machine perfusion (HMP) combined with hydrogen gas has previously been shown to mitigate ischemia-reperfusion injury (IRI) in rat liver, but without full recovery of function.
Yusuke Minami, Siddabasave Gowda B. B. Gowda, Kengo Shibata, Sodai Sakamoto, Divyavani Gowda, Tsuyoshi Shimamura, Akinobu Taketomi, Hitoshi Chiba, Moto Fukai, Shu-Ping Hui   +9 more
doaj   +1 more source

Surface loops of extracellular phospholipase A1 determine both substrate specificity and preference for lysophospholipids

Journal of Lipid Research, 2012
Members of the pancreatic lipase family exhibit both lipase activity toward triacylglycerol and/or phospholipase A1 (PLA1) activity toward certain phospholipids.
Naoaki Arima, Asuka Inoue, Kumiko Makide, Takamasa Nonaka, Junken Aoki   +4 more
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Characterization and relative quantification of phospholipids based on methylation and stable isotopic labeling[S]

Journal of Lipid Research, 2016
Phospholipids (PLs), one of the lipid categories, are not only the primary building blocks of cellular membranes, but also can be split to produce products that function as second messengers in signal transduction and play a pivotal role in numerous ...
Tanxi Cai, Qingbo Shu, Peibin Liu, Lili Niu, Xiaojing Guo, Xiang Ding, Peng Xue, Zhensheng Xie, Jifeng Wang, Nali Zhu, Peng Wu, Lili Niu, Fuquan Yang   +12 more
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Effects of Dietary Lysophospholipids on Growth Performance, Hepatic Lipid Metabolism, Intestinal Health and Dietary Lipid Levels of Largemouth Bass (Micropterus salmoides)

Fishes
This study investigated the effects of dietary lysophospholipids on growth performance, hepatic lipid metabolism, intestinal health, and dietary lipid levels of largemouth bass. The 56-day experiment included five groups: CON (0% lysophospholipids), LL50
Xiaorui Fan, Yuqiang Wei, Jianguo Zhao, Yajun Wang, Jianhua Zhao, Qiyou Xu   +5 more
doaj   +1 more source

Novel bisretinoids of human retina are lyso alkyl ether glycerophosphoethanolamine-bearing A2PE species

Journal of Lipid Research, 2018
Bisretinoids are a family of fluorophores that form in photoreceptor cells' outer segments by nonenzymatic reaction of two vitamin A aldehydes (A2) with phosphatidylethanolamine (PE).
Hye Jin Kim, Janet R. Sparrow
doaj   +1 more source

Cell type‐selective pathways and clinical associations of lysophosphatidic acid biosynthesis and signaling in the ovarian cancer microenvironment

Molecular Oncology, 2019
The peritoneal fluid of ovarian carcinoma patients promotes cancer cell invasion and metastatic spread with lysophosphatidic acid (LPA) as a potentially crucial mediator.
Silke Reinartz, Sonja Lieber, Jelena Pesek, Dominique T. Brandt, Alina Asafova, Florian Finkernagel, Bernard Watzer, Wolfgang Andreas Nockher, Andrea Nist, Thorsten Stiewe, Julia M. Jansen, Uwe Wagner, Anne Konzer, Johannes Graumann, Robert Grosse, Thomas Worzfeld, Sabine Müller‐Brüsselbach, Rolf Müller   +17 more
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LPA receptor signaling: pharmacology, physiology, and pathophysiology

Journal of Lipid Research, 2014
Lysophosphatidic acid (LPA) is a small ubiquitous lipid found in vertebrate and nonvertebrate organisms that mediates diverse biological actions and demonstrates medicinal relevance. LPA's functional roles are driven by extracellular signaling through at
Yun C. Yung, Nicole C. Stoddard, Jerold Chun   +2 more
doaj   +1 more source