Results 21 to 30 of about 7,391 (220)

Intravenous sphingosylphosphorylcholine protects ischemic and postischemic myocardial tissue in a mouse model of myocardial ischemia/reperfusion injury [PDF]

, 2010
HDL, through sphingosine-1-phosphate (S1P), exerts direct cardioprotective effects on ischemic myocardium. It remains unclear whether other HDL-associated sphingophospholipids have similar effects.
Bodo Levkau, Levkau, Bodo, Herrgott, Ilka, Johanning, Kai, Echtermeyer, Frank, Chun, Jerold, Hildebrand, Reinhard, Ilka Herrgott, Gregor Theilmeier, Christine Herzog, Winterhalter, Michael, Frank Ulrich Müller, Schmitz, Martina, Müller, Frank Ulrich, Jan Mersmann, Michael Winterhalter, Reinhard Hildebrand, Martina Schmitz, Herzog, Christine, Frank Echtermeyer, Jerold Chun, Theilmeier, Gregor, Mersmann, Jan, Larmann, Jan, Jan Larmann, Kai Johanning   +25 more
core   +1 more source

Treatment-Free Remission in Chronic Myeloid Leukemia: Toward Precision and Personalized Approaches to Functional Cure. [PDF]

Cancer Sci
Immune surveillance of residual leukemic stem cells after tyrosine kinase inhibitor discontinuation involves coordinated NK‐cell, CTL, Treg, pDC, and neutrophil activity that predicts treatment‐free remission, while exhausted CTLs and Treg expansion predict relapse in chronic myeloid leukemia.
Ureshino H, Kimura S.
europepmc   +2 more sources

Lysophosphatidylcholine-induced mitochondrial fission contributes to collagen production in human cardiac fibroblasts[S]

Journal of Lipid Research, 2019
Lysophosphatidylcholine (LPC) may accumulate in the heart to cause fibrotic events, which is mediated through fibroblast activation and collagen accumulation.
Hui-Ching Tseng, Chih-Chung Lin, Li-Der Hsiao, Chuen-Mao Yang   +3 more
doaj   +1 more source

The grease trap: uncovering the mechanism of the hydrophobic lid in Cutibacterium acnes lipase[S]

Journal of Lipid Research, 2020
Acne is one of the most common dermatological conditions, but the details of its pathology are unclear, and current management regimens often have adverse effects. Cutibacterium acnes is known as a major acne-associated bacterium that derives energy from
Hyo Jung Kim, Bong-Jin Lee, Ae-Ran Kwon
doaj   +1 more source

Mutations of OsPLDa1 Increase Lysophospholipid Content and Enhance Cooking and Eating Quality in Rice

Plants, 2020
Phospholipids belong to a significant class of lipids and comprise ~10% of total lipids in rice grains. Lysophospholipid (LPL) is derived from the hydrolysis of phospholipids and plays an important role in rice grain quality.
Muhammad Saad Shoaib Khan, Rasbin Basnet, Sulaiman Ahmed, Jinsong Bao, Qingyao Shu   +4 more
doaj   +1 more source

Lysophospholipid (S1P) receptors in GtoPdb v.2023.1 [PDF]

, 2023
Sphingosine 1-phosphate (S1P) receptors (nomenclature as agreed by the NC-IUPHAR Subcommittee on Lysophospholipid receptors [96]) are activated by the endogenous lipid sphingosine 1-phosphate (S1P). Originally cloned as orphan members of the endothelial
Victoria Blaho, Blaho, Victoria, Jonnalagadda, Deepa, Deepa Jonnalagadda, Chun, Jerold, Jerold Chun, Kihara, Yasuyuki, Deron Herr, Herr, Deron, Yasuyuki Kihara, Jones, Danielle, Danielle Jones   +11 more
core   +1 more source

Shedding new light on lipid biology with coherent anti-Stokes Raman scattering microscopy

Journal of Lipid Research, 2010
Despite the ubiquitous roles of lipids in biology, the detection of lipids has relied on invasive techniques, population measurements, or nonspecific labeling. Such difficulties can be circumvented by a label-free imaging technique known as coherent anti-
Thuc T. Le, Shuhua Yue, Ji-Xin Cheng
doaj   +1 more source

A Review of Cyclic Phosphatidic Acid and Other Potential Therapeutic Targets for Treating Osteoarthritis

Biomedicines, 2023
Osteoarthritis (OA), a chronic degenerative joint disease, is the most common form of arthritis. OA occurs when the protective cartilage that cushions the ends of bones gradually breaks down.
Tamotsu Tsukahara, Shigeyuki Imamura, Toshiro Morohoshi   +2 more
doaj   +1 more source

Dietary Supplementation of Lysophospholipids Affects Feed Digestion in Lambs

Animals, 2019
Five experiments were conducted to examine effects of lysophospholipids (LPL) on live weight gain, nutrient digestibility, ruminal fermentation parameters, serum biochemical parameters and rumen bacterial community profile in fattening lambs. Two dietary
Qin Huo, Bo Li, Long Cheng, Tingting Wu, Peihua You, Shuanghua Shen, Yiyong Li, Yuhua He, Wannian Tian, Rongquan Li, Changsheng Li, Jianping Li, Baijun Song, Chunqing Wang, Xuezhao Sun   +14 more
doaj   +1 more source

Current Knowledge on Mammalian Phospholipase A₁, Brief History, Structures, Biochemical and Pathophysiological Roles

Molecules, 2022
Phospholipase A1 (PLA1) is an enzyme that cleaves an ester bond at the sn-1 position of glycerophospholipids, producing a free fatty acid and a lysophospholipid.
Shun Yaginuma, Hiroki Kawana, Junken Aoki   +2 more
doaj   +1 more source