Results 131 to 140 of about 88,611 (239)

Unveiling Value in Plastic Waste: Synthesis of 1,3‐Dioxolan‐4‐ones from Polylactic Acid and Polyoxymethylene to Enhance Plastic Biodegradation

open access: yesAdvanced Synthesis &Catalysis, Volume 368, Issue 7, 1 April 2026.
An acid‐catalyzed process provides a robust method to upcycle even impure and colored PLA and POM plastic waste into high‐value DOXs. Incorporating these DOXs enables the synthesis of PLLA materials that exhibit enhanced biodegradability, surpassing the performance of cellulose.
Mi‐hyun Lee   +7 more
wiley   +1 more source

Adherence to the Mediterranean and Mediterranean‐Dietary Approaches to Stop Hypertension Intervention for Neurodegenerative Delay (MIND) Diets and Parkinson's Disease Incidence in Women: Results from the Prospective E3N Cohort

open access: yesAnnals of Neurology, Volume 99, Issue 4, Page 1014-1029, April 2026.
Objective The evidence regarding adherence to dietary patterns and Parkinson's disease (PD) risk is inconsistent. Because of the long prodromal PD phase, reverse causation represents a major threat to investigations of diet in relation to PD. We examined whether adherence to the Mediterranean (MED) and Mediterranean‐Dietary Approaches to Stop ...
Mariem Hajji‐Louati   +6 more
wiley   +1 more source

Untargeted Metabolomics Identifies N‐Lactoyl‐Amino Acids as Dose‐Responsive Plasma Biomarkers of Metformin Adherence in Type 2 Diabetes

open access: yesClinical Pharmacology &Therapeutics, Volume 119, Issue 4, Page 1057-1069, April 2026.
Metformin is the most widely prescribed antidiabetic drug, yet adherence remains difficult to objectively assess. Using untargeted metabolomics and lipidomics, we analyzed plasma from 637 patients with type 2 diabetes (T2D) with confirmed metformin use and 143 nondiabetic controls, annotating 614 metabolites.
Tomas Cajka   +12 more
wiley   +1 more source

Neuronal Activity Promotes Node‐Like Cluster Assembly Prior to Myelination and Remyelination in the Central Nervous System

open access: yesGlia, Volume 74, Issue 4, April 2026.
Ronzano et al. show that neuronal activity promotes node‐like cluster (NLC) formation before (re)myelination by regulating β1Nav and Nav1.1, which are essential for NLC assembly. This may represent an intermediate step in activity‐driven myelination and contribute to the regulation of axonal conduction.
Rémi Ronzano   +10 more
wiley   +1 more source

Relational Healing: Survivors of Sex Trafficking and Their Experiences of Connection, Disconnection, and Growth

open access: yesJournal of Counseling &Development, Volume 104, Issue 2, Page 280-292, April 2026.
ABSTRACT In this interpretive phenomenological analysis, we interviewed 10 women to make meaning of their lived experiences of sex trafficking and mental health challenges and how relational dynamics influenced their healing and sense of self. Our analysis revealed four themes: (a) central relational paradox, which described internalized shame and ...
Claudia G. Interiano‐Shiverdecker   +3 more
wiley   +1 more source

Bicarbonate and Other Buffer Therapies in Acute Metabolic Acidosis: A Systematic Review and Meta‐Analysis

open access: yesActa Anaesthesiologica Scandinavica, Volume 70, Issue 4, April 2026.
ABSTRACT Background The aim of this study was to perform a systematic review and meta‐analysis on the effect of buffering therapies on clinical outcomes in adult patients with acute metabolic acidosis. Methods Searches were conducted in Embase, Cochrane, and PubMed for randomised clinical trials comparing a buffering therapy to either placebo, no ...
Peter C. Lind   +5 more
wiley   +1 more source

Intentional Negotiation and Filling of Accessory Canals: A Case Series With Three‐Dimensional Segmentation and Volumetric Healing Assessment

open access: yesInternational Endodontic Journal, Volume 59, Issue 4, Page 728-736, April 2026.
ABSTRACT Introduction Accessory canals (ACs) are anatomical features that may harbour residual infected tissue and contribute to persistent periradicular inflammation. Although filling of these structures is occasionally achieved passively, their intentional mechanical negotiation remains rarely documented in clinical practice. This case series aims to
Lucas Pinto Carpena   +3 more
wiley   +1 more source

Epigenetic Modulation of the ACE System Underlies the Slow Aerobic Muscle Phenotype and Metabolic Exercise Response

open access: yesThe FASEB Journal, Volume 40, Issue 6, 31 March 2026.
Weekly moderate‐to‐vigorous activity (≈6 h) induced a marked increase in ACE promoter methylation in exercised knee‐extensor muscle. In combination with the ACE I/D genotype, ACE methylation contributed to ACE gene activity regulation in ways aligning with the slow‐twitch, aerobic muscle phenotype and its metabolic response to endurance exercise ...
Flück Martin   +2 more
wiley   +1 more source

Laser‐Induced Microfabrication of Carbon Nanostructure: Processing Mechanism and Application for Next‐Generation Battery Technology

open access: yesAdvanced Functional Materials, Volume 36, Issue 19, 5 March 2026.
The article reviews laser‐processed carbons from various precursors, processing mechanism and their application in advanced batteries. The laser process is chemical free, fast, and scalable, enabling improved battery performance and stability for Li, Na, and Zn battery technologies.
Sujit Deshmukh   +2 more
wiley   +1 more source

Microglial HVCN1 Deficiency Improves Movement and Survival of SOD1G93A ALS Mice by Enhancing Microglial Migration and Neuroprotection

open access: yesAdvanced Science, Volume 13, Issue 13, 3 March 2026.
Hydrogen voltage gated channel 1 (HVCN1) is upregulated in microglia of both ALS patients and its mouse model. HVCN1 deficiency enhances microglial migration via suppressing Akt signaling, promotes neurotrophic capacity and motor function, and prolongs survival of the SOD1G93A ALS mice. This study identifies HVCN1 as a novel, promising druggable target
Fan Wang   +16 more
wiley   +1 more source

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