Results 131 to 140 of about 88,471 (245)

Prostaglandin D2 Synthase Controls Schwann Cells Metabolism and Peripheral Myelin Homeostasis

Glia, Volume 74, Issue 3, March 2026.
Prostaglandin D2 Synthase (L‐PGDS) controls PPNS myelin lipids’ composition and Schwann cells energetic metabolism In the absence of L‐PGDS Schwann cells turn to acetate as the main energetic source. These metabolic changes result in ketone bodies production to preserve neuronal survival.
Amelia Trimarco, Matteo Audano, Rosa La Marca, Marta Pellegatta, Paolo Canevazzi, Mariaconcetta Cariello, Marta Falco, Silvia Pedretti, Gabriele Imperato, Alessandro Cestaro, Paola Podini, Giorgia Dina, Angelo Quattrini, Luca Massimino, Donatella Caruso, Nico Mitro, Carla Taveggia   +16 more
wiley   +1 more source

The Grey Zone Project: Risk‐Based Classification of ABCD1 Variants in X‐Linked Adrenoleukodystrophy

Journal of Inherited Metabolic Disease, Volume 49, Issue 2, March 2026.
ABSTRACT Newborn screening (NBS) for X‐linked adrenoleukodystrophy (ALD) enables early identification of boys at risk for adrenal insufficiency (AI) and cerebral ALD (CALD). However, NBS frequently identifies ABCD1 variants of uncertain significance (VUS), which are associated with only borderline‐elevated C26:0‐lysophosphatidylcholine (LPC(26:0 ...
Troy C. Lund, Kelly Miettunen, Yorrick R. J. Jaspers, Caroline Bergner, Joshua L. Bonkowsky, Fabio Bruschi, Julie S. Cohen, Inge M. E. Dijkstra, Florian S. Eichler, Eric J. Mallack, Gajja S. Salomons, Robert Thompson, Davide Tonduti, Keith P. van Haren, Mirjam M. C. Wamelink, Ayelet Zerem, Marc Engelen, Stephan Kemp   +17 more
wiley   +1 more source

The Representativeness of the Annual Survey of Hours and Earnings and Its Implications for UK Wage Policy

British Journal of Industrial Relations, Volume 64, Issue 1, Page 21-36, March 2026.
ABSTRACT The Annual Survey of Hours and Earnings (ASHE) is based on an annual 1% sample of employee jobs and provides many of the UK's official earnings statistics. These statistics are produced using official weights designed to make the achieved sample in each year representative of the population of employee jobs in Britain by gender, age ...
John Forth, Alex Bryson, Van Phan, Felix Ritchie, Carl Singleton, Lucy Stokes, Damian Whittard   +6 more
wiley   +1 more source

Understanding the dynamic nature of plant lipid anabolic and catabolic metabolism is key to sustainable oilseed engineering

New Phytologist, Volume 249, Issue 5, Page 2196-2214, March 2026.
Summary Plant‐derived oils are essential sources of reduced carbon and various fatty acid (FA) structures for food, biofuels, and the oleochemical industry. Despite extensive efforts, engineering mainstream oilseed crops to produce high levels of industrially valuable unusual FAs (UFAs) remains challenging.
Prasad Parchuri, Sean T. McGuire, Matthew G. Garneau, Niña Alyssa M. Barroga, Philip D. Bates   +4 more
wiley   +1 more source

Comparison of Mechanical Properties of Lignin/High‐Density Polyethylene (HDPE) Composites and Wood/HDPE Composites

Journal of Applied Polymer Science, Volume 143, Issue 5, February 5, 2026.
Manufacturing process and mechanical testing of lignin polymer composites. ABSTRACT Lignin is a plant‐derived, the second most abundant natural polymer, and a waste byproduct of the pulp industry. Incorporation of lignin into plastic composites using scalable approaches is commercially favored and low carbon‐cost.
Yelin Ni, Madhusudhan R. Pallaka, Jose Ramos, Ethan K. Nickerson, Jaelynne A. King, Satish Nune, Keerti S. Kappagantula, David Heldebrant   +7 more
wiley   +1 more source

Relapsing–Remitting Multiple Sclerosis Is Associated With a Dysbiotic Oral Microbiome

Annals of Clinical and Translational Neurology, Volume 13, Issue 2, Page 256-269, February 2026.
ABSTRACT Objective Multiple sclerosis (MS) is a chronic autoimmune disorder characterized by inflammation, demyelination, and neurological impairment. While the gut microbiota's role in MS is extensively studied, the association between the oral microbiota and MS remains underexplored, particularly in North American cohorts.
Sukirth M. Ganesan, Meeta Yadav, Sudeep Ghimire, Peter C. Lehman, Apurva J. Patel, Sydney Woods, Heena Olalde, Jemmie Hoang, Mishelle Paullus, Catherine Cherwin, Christine Gill, Tracey Cho, Ashutosh K. Mangalam   +12 more
wiley   +1 more source

Capture of Saprolegnia parasitica Spores in Flow‐Through Aquaculture: First Observations

Aquaculture, Fish and Fisheries, Volume 6, Issue 1, February 2026.
ABSTRACT Saprolegniosis, typically induced by oomycete Saprolegnia parasitica, is one of the most difficult pathogens in fish and other aquatic animals in freshwater systems. It is especially harmful for the endangered species landlocked salmon (Salmo salar m. sebago).
Petra Camilla Lindholm‐Lehto, Katri S. Kontturi, Kristoffer Meinander, Hannes Orelma   +3 more
wiley   +1 more source

Neural Dynamics of Attentional Boost Effect

Brain and Behavior, Volume 16, Issue 2, February 2026.
An ERP study reveals a distinct neural timeline of enhanced processing for target‐paired stimuli, from encoding to recognition, supporting the mechanism of target enhancement over distractor inhibition. ABSTRACT Background: The attentional boost effect refers to enhanced memory for information presented concurrently with target detection.
Xintong Chen, Xuan Lyu, Li Zhu, Qin Cui, Qing Yang, Xinglin Li, Kaiye Xiang, Chun Zheng, Chao Fu   +8 more
wiley   +1 more source

Digital Biomarkers for Precision Early Detection of Lung Cancer: Integrating AI‐Driven Multi‐Omics Into Clinical Pathways

Cancer Medicine, Volume 15, Issue 2, February 2026.
ABSTRACT Background Lung cancer remains the leading cause of cancer‐related mortality worldwide, highlighting the urgent need for earlier detection within real‐world screening and patient management pathways. Recent advances in multi‐omics technologies have created new opportunities for identifying biomarkers associated with early‐stage lung cancer ...
Fan Bu, Zhi‐Qiang Ling
wiley   +1 more source

LPC-engineered liposomes activate transcytosis for paclitaxel brain delivery and potentiation of TTFields/TMZ via TALECT regimen in glioblastoma. [PDF]

Theranostics
Zhan Q, Yi K, Yang S, Hong B, Su D, Zhao J, Wang Q, Cui X, Huang Y, Ding Y, Cheng C, Ju J, Kang C.   +12 more
europepmc   +1 more source