Results 141 to 150 of about 88,471 (245)

Risk Factors and Prediction Model for Early‐Onset Immune‐Related Adverse Events in Pan‐Cancer Patients Undergoing Anti‐PD‐(L)1 Therapy: A Retrospective Study in a Tertiary‐Level Hospital

Cancer Medicine, Volume 15, Issue 2, February 2026.
ABSTRACT Background Anti‐programmed death 1 (PD‐1) and anti‐programmed death ligand 1 (PD‐L1) immune checkpoint inhibitors (ICIs) have changed the treatment landscape of many advanced malignancies. However, immune‐related adverse events (irAEs) bring great challenges to clinical benefits. The prediction of irAEs is urgently demanded for early detection
Panpan Jiao, Lijuan Xue, Weijuan Tan, Quan Chen, Shan Lin, Min Song, Chunling Ma, Juan Zhan   +7 more
wiley   +1 more source

New School Safety Legislation and its Impact on K-12 School Personnel [PDF]

, 2011
Calley, Nancy G., Ph.D., LPC
core   +2 more sources

Metabolic reprogramming of efferocytosis in the tumour microenvironment: From apoptotic‐cell clearance to therapeutic targeting

Clinical and Translational Medicine, Volume 16, Issue 2, February 2026.
This review systematically deconstructs the pathological efferocytic—metabolic axis in tumours, framing it as a three‐stage, self‐reinforcing cycle: from metabolite‐driven macrophage recruitment, through hijacked surface recognition, to post‐phagocytic metabolic reprogramming that locks in immunosuppression.
Qianlu Yang, Jie Yan, Qianxi Yang
wiley   +1 more source

Intelligent Multi‐Mode DC Fast Charging System for Urban EV Infrastructure With Adaptive Control and Dynamic Load Management

Engineering Reports, Volume 8, Issue 2, February 2026.
This study introduces a cost‐effective and energy‐efficient DC Partial Charging Facility (DCPCF) for urban EV charging. Featuring three user‐defined modes, it ensures reliable operation, scalable design, and suitability for resource‐limited environments, making it ideal for roadside, hotel, and parking lot installations.
M. Subashini, V. Sumathi
wiley   +1 more source

Lysophosphatidylcholine as a Novel Diagnostic Biomarker in Kawasaki Disease: Based on Immunometabolism-Related Signature. [PDF]

J Inflamm Res
Ma X, Zheng Y, Feng C, Zhang M, Wang H, Li X.   +5 more
europepmc   +1 more source

Panax notoginseng Saponins Ameliorate High‐Fat Diet‐Induced Liver Injury via Mechanisms Involving TLR4‐Mediated Signaling and Lipid Metabolism

Food Science &Nutrition, Volume 14, Issue 2, February 2026.
Panax notoginseng saponins (PNS) ameliorate high‐fat diet‐induced liver injury by modulating the LPS‐TLR4/MyD88 axis. This leads to the concurrent suppression of NF‐κB and MAPK signaling, which reduces oxidative stress and inflammation while improving lipid metabolism.
Rong Li, Junyu Ma, Mengyao Li, Bangzhao Zeng, Xuexun Li, Xiaoyan Bi, Xin Zhao, Qin Gao, Yanling Yao, Yang Jiang, Chunmei Zhang, Fuli Ya   +11 more
wiley   +1 more source

Phosphatidylcholine with C26:0 moiety, a precursor of a diagnostic marker for X-ALD, is synthesized by LPLAT10/LPEAT2. [PDF]

J Lipid Res
Hama K, Fujiwara Y, Imai K, Kusakabe Y, Hayashi Y, Takashima S, Azuma S, Kondo M, Yamashita A, Takita R, Shimozawa N, Yokoyama K.   +11 more
europepmc   +1 more source

Dose‐Dependent Biphasic Effect of Palmitic Acid on Oligodendrocyte Function: Impacts on Viability, Differentiation, and Myelination

Journal of Cellular Physiology, Volume 241, Issue 2, February 2026.
Schematic diagram showing dose‐dependent effects of PA in oligodendrocyte precursor MO3.13 cells and rodent organotypic hippocampal and cerebellar slice cultures. High doses lead to cell death accompanied by mitochondrial impairment, whereas low doses activate the Nrf2 antioxidant response and exert neuroprotective effect while balancing mitochondrial ...
Anna Palmiero, Luca Pipicelli, Giuliana La Rosa, Concetta Sozio, Carolina Punziano, Maddalena Raia, Raffaella Faraonio, Giovanna Vitolo, Mariarosaria Cammarota, Francesca Boscia, Ciro Menale, Mariarosaria Santillo, Simona Damiano   +12 more
wiley   +1 more source

Lipidomic Analysis of Plasma Extracellular Vesicles from Adiponectin Deficient Mice or Metabolic Syndrome Patients Reveals Pro‐Oxidative and Pro‐Inflammatory Lipid Signatures Correlating with Metabolic Dysfunction

Journal of Extracellular Vesicles, Volume 15, Issue 2, February 2026.
Adiponectin deficiency remodels the lipid composition of plasma extracellular vesicles (EV), enriching polyunsaturated phospholipids and reducing lysophospholipids. These remodelled EV impact oxidative, inflammatory and metabolic function in recipient cells.
Sungji Cho, Hye Kyoung Sung, Khang Nguyen, Yubin Lei, Sivaporn Wannaiampikul, Brian Lee, Eddie Tam, Yihan Luo, Evgeniy V. Petrotchenko, Christoph H. Borchers, Kacey J. Prentice, Scott A Summers, Dylan Burger, Gary Sweeney   +13 more
wiley   +1 more source

TREM-1 inhibitor specificity and timing of treatment initiation can impact its therapeutic efficacy in cancer and inflammatory disease. [PDF]

Front Oncol
Sigalov AB.
europepmc   +1 more source