Results 261 to 270 of about 1,828,400 (307)

Gene expression profiles in liver of zebrafish treated with microcystin-LR

Environmental Toxicology and Pharmacology, 2008
Microcystin-LR (MC-LR) is the most frequently studied cyclic heptatoxin produced by cyanobacteria, which has tremendous negative impacts on fish, while its molecular mechanism behind remained unclear at present. Here, Affymetrix Zebrafish GeneChip was used to identify alterations in gene expression of zebrafish (Danio rerio) after MC-LR exposure. Among
Lili, Wei, Baojian, Sun, Lirong, Song, Pin, Nie   +3 more
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Transcriptional responses of glutathione transferase genes in Ruditapes philippinarum exposed to microcystin-LR

, 2014
No abstracts are to be cited without prior reference to the author. Microcystins (MCs) are potent hepatotoxins produced by bloom-forming species of toxic cyanobacteria. Among these, MC-LR is the most commonly found and toxic variant. Bivalves, due to their benthic and sedentary mode of life, are one of the most threatened organisms by these ...
Reis, Bruno, Carneiro, Mariana, Azevedo, Joana, Vasconcelos, Vítor, Martins, José Carlos   +4 more
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Identification of apoptosis-related genes and transcription variations in response to microcystin-LR in zebrafish liver

Toxicology and Industrial Health, 2012
There is growing evidence that the effects of microcystin-LR (MC-LR) are closely related to apoptosis. This study utilized microarray to identify the apoptosis-related genes induced by MC-LR in zebrafish liver. The messenger RNA abundance of some apoptosis-related genes was found to be increased, including five tumor necrosis factor (TNF)-related ...
Lili, Wei, Dave, Hoole, Baojian, Sun
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Molecular markers and phenotypic characterization of adult plant resistance genes Lr 34, Lr 46, Lr 67 and Lr 68 and their association with partial resistance to leaf rust in wheat

Journal of Genetics, 2019
Thirty-nine wheat genotypes were studied to estimate their partial resistance levels to leaf rust at Behira governortae during three growing seasons, i.e. 2016/2017, 2017/2018 and 2018/2019. In these genotypes, partial resistance was characterized using final leaf rust severity (FRS %) and area under disease progress curve (AUDPC).
Walid M, El-Orabey, Aladdin, Hamwieh, Shaimaa M, Ahmed   +2 more
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Gene expression modulation by heat stress in Acidithiobacillus ferrooxidans LR

Antonie van Leeuwenhoek, 2011
During bioleaching, Acidithiobacillus ferrooxidans is subjected to different types of stress, including heat stress, which affect bacterial growth. In this work, real time quantitative PCR was used to analyze the expression of heat shock genes, as well as genes that encode proteins related to several functional categories in A. ferrooxidans. Cells were
Daniela A, Ribeiro, Lúcio F C, Ferraz, Renato, Vicentini, Laura M M, Ottoboni   +3 more
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Estimation of the gene pool of the CIMMYT collection winter bread wheat on presence of the Lr 34 gene

2021
Nowadays in Russia and in the world, the problem of improving food security is becoming more and more urgent. One of the main crops grown worldwide is winter bread wheat. Varieties resistant to main leaf diseases can produce large grain yields. Thus, the study and identification of resistance genes are of great importance.
О. S. Zhogaleva, А. Yu. Dubina, N. T. Kupreyshvili, S. V. Podgorny   +3 more
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Effects of microcystin-LR on bacterial and fungal functional genes profile in rat gut

Toxicon, 2015
The short-term exposure to microcystin-LR (MC-LR, one of the most common and toxic variants generated by toxigenic cyanobacteria) induced gut dysfunction such as generation of reactive oxygen species, cell erosion and deficient intestinal absorption of nutrients.
Juan, Lin, Jun, Chen, Jun, He, Jing, Chen, Qingyun, Yan, Jizhong, Zhou, Ping, Xie   +6 more
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Characterisation of a gene cluster involved in bacterial degradation of the cyanobacterial toxin microcystin LR

Environmental Toxicology, 2001
AbstractA novel pathway for degradation of the cyanobacterial heptapeptide hepatotoxin microcystin LR was identified in a newly isolated Sphingomonas sp. (Bourne et al. 1996 Appl. Environ. Microbiol. 62: 4086–4094). We now report the cloning and molecular characterisation of four genes from this Sphingomonas sp.
Bourne, David G., Riddles, Peter, Jones, Gary J., Smith, Wendy, Blakeley, Robert L.   +4 more
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Red blood cell PK deficiency: An update of PK-LR gene mutation database

Blood Cells, Molecules, and Diseases, 2016
Pyruvate kinase (PK) deficiency is known as being the most common cause of chronic nonspherocytic hemolytic anemia (CNSHA). Clinical PK deficiency is transmitted as an autosomal recessive trait, that can segregate neither in homozygous or in a compound heterozygous modality, respectively.
Canu G, De Bonis M, Minucci A, Capoluongo E   +3 more
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Molecular characterization of the PK‐LR gene in sixteen pyruvate kinase‐deficient patients

British Journal of Haematology, 2001
We studied the PK‐LR gene in 16 unrelated patients with congenital haemolytic anaemia associated with erythrocyte pyruvate kinase deficiency. Fifteen different mutations were detected among the 28 mutated alleles identified: two deletions (del 1010G, del 1042–1044); one four nucleotide duplication (nt 1515–1518, GGTC); one splice site [IVS6(−2)t]; nine
Zanella, Alberto, Bianchi, Paola, Fermo, Elisa, Iurlo, Alessandra, Zappa, Manuela, Vercellati, Cristina, Boschetti, Carla, Baronciani, Luciana, Cotton, Frédéric   +8 more
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