Results 271 to 280 of about 1,828,400 (307)

Identification of thalassemia gene cluster deletion by long‐read whole‐genome sequencing (LR‐WGS)

International Journal of Laboratory Hematology, 2021
AbstractIntroductionAt present, a variety of molecular detection methods are obtained to diagnose thalassemia accurately. Although exome sequencing or specific panels have been widely used in clinical diagnosis of genetic diseases, the positive rate is about 25%‐30%.
Fan Jiang, Gui‐Zhen Lyu, Victor Wei Zhang, Dong‐Zhi Li   +3 more
openaire   +2 more sources

Cloning and expression of the first gene for biodegrading microcystin LR by Sphingopyxis sp. USTB-05

Journal of Environmental Sciences, 2012
Harmful cyanobacterial blooms are a growing environmental problem worldwide in natural waters, the biodegradation is found to be the most efficient method for removing microcystins (MCs) produced by harmful cyanobacteria. Based on the isolation of a promising bacterial strain of Sphingopyxis sp.
Hai, Yan, Huasheng, Wang, Junfeng, Wang, Chunhua, Yin, Song, Ma, Xiaolu, Liu, Xueyao, Yin   +6 more
openaire   +2 more sources

ASSESSMENT OF FIELD RESISTANCE AND IDENTIFICATION OF SOME LR-GENES IN SPRING TRITICALE SAMPLES

Izvestiâ Timirâzevskoj selʹskohozâjstvennoj akademii, 2020
The paper presents the results of studying the field resistance of a large number of spring triticale samples to brown rust pathogen under the natural infectious background of the Moscow pathogen population in 2012–2015, as well as the identification of some effective Lr-genes in these samples.
I.V. GRUZDEV, P.YU. KROUPIN, L.S. BOLSHAKOVA, M.G. DIVASHUK, A.A. SOLOVIEV   +4 more
openaire   +1 more source

Red cell pyruvate kinase deficiency: 17 new mutations of the PK‐LR gene

British Journal of Haematology, 2005
SummaryThe PK‐LR gene was studied in 23 patients with congenital haemolytic anaemia associated with erythrocyte pyruvate kinase (PK) deficiency. Twenty‐seven different mutations were detected among the 42 mutated alleles identified: 19 missense mutations, four splice site mutations and one nonsense, one single base deletion and two large deletions ...
FERMO E, BIANCHI P, COTTON F, VERCELLATI C, WRITZL K, BAKER K, HANN I, RODWELL R, ZANELLA A., CHIARELLI, LAURENT, VALENTINI, GIOVANNA   +10 more
openaire   +4 more sources

Leaf Rust‐Resistance Genes Lr41, Lr42, and Lr43 Transferred from Triticum tauschii to Common Wheat

Crop Science, 1994
In order to diversify the genetic base of resistance in hard red winter wheat (Triticum aestivum L.) to leaf rust (caused by Puccinia recondita Rob. ex Desm.), five genes for resistance were transferred from the diploid goatgrass T. tauschii (Coss.) Schmal. to hexaploid wheat lines.
T. S. Cox, W. J. Raupp, B. S. Gill
openaire   +1 more source

CUDA-LR: CUDA-accelerated logistic regression analysis tool for gene-gene interaction for genome-wide association study

2011 IEEE International Conference on Bioinformatics and Biomedicine Workshops (BIBMW), 2011
In genome-wide association studies (GWAS), logistic regression (LR) has been most commonly used for finding an association between a disease phenotype and genetic variants such as single nucleotide polymorphism (SNP). Since logistic regression model requires iterative algorithms to get the parameter estimates, its application to GWAS has been limited ...
Sungyoung Lee 0002, Min-Seok Kwon, Ik-Soo Huh, Taesung Park   +3 more
openaire   +1 more source

Differential gene expression in Acidithiobacillus ferrooxidans LR planktonic and attached cells in the presence of chalcopyrite

Journal of Basic Microbiology, 2014
Acidithiobacillus ferrooxidans is commonly used in bioleaching operations to recover copper from sulfide ores. It is commonly accepted that A. ferrooxidans attaches to mineral surfaces by means of extracellular polymeric substances (EPS), however the role of type IV pili and tight adherence genes in this process is poorly understood.
Ossa Henao, Diana Marcela, Vicentini, Renato, Rodrigues, Viviane Drumond, Bevilaqua, Denise, Mariscal Ottoboni, Laura Maria   +4 more
openaire   +3 more sources

Screening of leaf rust resistance genes (Lr) in the breeding lines of winter bread wheat

2022
En la región de Rostov, entre los cultivos de cereales, el trigo de invierno ocupa una posición de liderazgo en términos de área sembrada. Los obtentores han desarrollado variedades de trigo, cuyo potencial de productividad es 1,5-2 veces mayor que su rendimiento real en producción.
О. S. Zhogaleva, O. V. Shumskaya, А. Yu. Dubina   +2 more
openaire   +1 more source

Alterations in transcription and protein expressions of HCC-related genes in HepG2 cells caused by microcystin-LR

Toxicology in Vitro, 2017
Microcystin-LR (MC-LR) is the most common and toxic hepatotoxin and it could induce human hepatitis and hepatocellular carcinoma (HCC) via the route of drinking water. The aim of the present study was to determine the expressions of oncogenes c-fos, c-jun, c-myc, c-met, and N-ras and tumor suppressor gene PTEN in HepG2 cells following MC-LR-exposure to
Xiaoyu, Li, Xiangyang, Zhang, Wenjie, Xie, Chune, Zhou, Yao, Li, Xiuhua, Zhang   +5 more
openaire   +2 more sources

Microcystin-LR synthesis as response to nitrogen: transcriptional analysis of the mcyD gene in Microcystis aeruginosa PCC7806

Ecotoxicology, 2010
The influence of environmental factors on microcystin production by toxic cyanobacteria has been extensively studied. However, the effect of nitrogen on the synthesis of this toxin remains unclear because of the literature contradictory data. The aim of this work was to determine how nitrate affects the transcriptional response of mcyD gene and the ...
Emma, Sevilla, Beatriz, Martin-Luna, Laura, Vela, M Teresa, Bes, M Luisa, Peleato, Maria F, Fillat   +5 more
openaire   +2 more sources