Results 41 to 50 of about 1,960,539 (306)

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Effects of pure microcystin-LR on the transcription of immune related genes and heat shock proteins in larval stage of zebrafish (Danio rerio)

open access: yes, 2009
Microcystins (MCs) are cyanobacterial toxins in water blooms that have received increasing attention as a public biohazard for human and animal health.
Li, Yuan   +4 more
core   +1 more source

BREEDING OF WINTER WHEAT ON TOLERANCE TO LEAF RUST (PUCCINIA TRITICINA ERIKS.) IN MOSCOW RIA “NEMCHINOVKA”

open access: yesЗерновое хозяйство России, 2018
The genes of P.triticina tolerance of the varieties of soft winter wheat have been studied by test-isolators. The experiment was based on Flor’s theory ‘gene for gene’, when a tolerant gene matches virulence.
B. I. Sandukhadze   +5 more
doaj   +2 more sources

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani   +9 more
wiley   +1 more source

Proton and Iron Binding by the Cyanobacterial Toxin Microcystin-LR

open access: yes, 2013
MDFRC item.Microcystins (MCs) are a group of hepatotoxins produced by cyanobacteria that have not had their functional role or the environmental factors that trigger production clearly determined. One suggestion is that microcystins are siderophores (i.e.
Klein, Annaleise R (14795218)   +5 more
core   +2 more sources

Postulation of seedling leaf rust resistance genes in 84 Chinese winter wheat cultivars

open access: yesJournal of Integrative Agriculture, 2015
Wheat leaf rust (caused by Puccinia triticina) is one of the most important fungal diseases in China. There are tens of winter wheat cultivars which are approved to be released by the government at a national level and more than 100 wheat cultivars at ...
Xiao-li REN   +4 more
doaj   +1 more source

Wheat leaf rust (Puccinia triticina Eriks.) virulence frequency and detection of resistance genes in wheat cultivars registered in the Czech Republic in 2016-2018

open access: yesCzech Journal of Genetics and Plant Breeding, 2020
In 2016-2018 virulence of the Czech wheat leaf rust population was studied on Thatcher near-isogenic lines, carrying different Lr genes, and 130 leaf rust isolates. Virulence to Lr9 was found only sporadically. Virulence frequency to Lr2a, Lr2b, Lr2c and
Alena Hanzalová   +2 more
doaj   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

open access: yesFEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu   +5 more
wiley   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

open access: yesFEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo   +4 more
wiley   +1 more source

Physiologic specialization of Puccinia triticina Erikss. and effectiveness of Lr genes in Bulgaria [PDF]

open access: yes, 2021
 Leaf rust caused by Puccinia triticina Erikss. is the most common diseases on wheat in Bulgaria. Monitoring on the pathogen population is carried out annually, and the information concerning the changes occurring in it and the data on the ...
Ivanova, Vanya   +2 more
core  

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