Results 61 to 70 of about 1,960,539 (306)
A Two‐Stage Plasma Biomarker Algorithm Reduces Amyloid PET Use and the p‐Tau217 Gray Zone
ABSTRACT Objective Plasma p‐Tau217 leaves 30%–50% of patients in an indeterminate “gray zone” often requiring Aβ‐PET. We developed GRAD (Gatekeeper‐Reflex for Alzheimer's Disease), a two‐stage Aβ‐positivity prediction model to improve classification while reserving Aβ‐PET for residual uncertainty.
Harthik Parankusham +7 more
wiley +1 more source
Chlorine/UV Process for Decomposition and Detoxification of Microcystin-LR
Microcystin-LR (MC-LR) is a potent hepatotoxin that is often associated with blooms of cyanobacteria. Experiments were conducted to evaluate the efficiency of the chlorine/UV process for MC-LR decomposition and detoxification.
Ernest R. Blatchley III (1345986) +6 more
core +1 more source
Microcystin-LR (MC-LR) exists widely in polluted food and water in humid and warm areas, and facilitates the progression of colorectal cancer (CRC). However, the molecular mechanism associated with the MC-LR-induced CRC progression remains elusive.
Yao Tan (519662) +9 more
core +1 more source
The results of experimental studies on field resistance of spring common wheat ( Triticum aestivum L . ) varieties to leaf rust in the Central Region of the Non-Black Soil Zone of Russia were described. Fifteen spring wheat varieties were evaluated under
Boburjon B. Najodov +2 more
doaj +1 more source
Identification and characteristics of wheat Lr orthologs in three rye inbred lines.
The genetic background of the immune response of rye to leaf rust (LR), although extensively studied, is still not well understood. The recent publication of the genome of rye line Lo7 and the development of efficient transcriptomic methods has aided the
Tomasz Krępski +5 more
doaj +1 more source
β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio +11 more
wiley +1 more source
Harmful cyanobacteria blooms may deteriorate freshwater environments, leading to bad water quality that can adversely affect the health of humans, animals, and aquatic life.
Michelline Kansole, Tsair-Fuh Lin
core +1 more source
Wheat provides staple food and industrial raw material for humans and animals, but its production decreased due to leaf rust (Lr) disease caused by Puccinia triticina by up to 15%.
Muhammad Farhan +4 more
doaj +1 more source
Core Ideas The emergence of new virulent Puccinia triticina races requires a continuous search for novel sources of resistance to combat leaf rust (LR) disease Twenty‐two wheat genotypes resistant to four P.
Suraj Sapkota +5 more
doaj +1 more source
Genetically Programmed Shape‐Morphing of Engineered Living Materials
Here, bacterial and mammalian engineered living materials (ELMs) are presented, in which living cells direct genetically programmed and enzymatically mediated shape‐morphing. The resulting deformation and shape‐recovery can be actuated in a genetically controlled manner by an ELM incorporating out‐of‐equilibrium counteracting biochemical reactions with
Jan Becker +7 more
wiley +1 more source

