Results 21 to 30 of about 96,524 (256)

Mass Spectrometry Evaluation of Biomarkers in the Vitreous Fluid in Gaucher Disease Type 3 with Disease Progression Despite Long-Term Treatment

Diagnostics, 2020
Intraocular lesions have been infrequently reported in patients with Gaucher disease type 3 (GD3). We previously reported siblings with GD3 who responded well to the combination of enzyme replacement therapy (ERT) and substrate reduction therapy (SRT ...
Aizeddin Mhanni, Michel Boutin, Frank Stockl, Janine Johnston, Jeff Barnes, Donald Duerksen, Leanne Zimmer, Christiane Auray-Blais, Cheryl Rockman-Greenberg   +8 more
doaj   +1 more source

A non-hallucinogenic LSD analog with therapeutic potential for mood disorders

Cell Reports, 2023
Summary: Hallucinations limit widespread therapeutic use of psychedelics as rapidly acting antidepressants. Here we profiled the non-hallucinogenic lysergic acid diethylamide (LSD) analog 2-bromo-LSD (2-Br-LSD) at more than 33 aminergic G protein-coupled
Vern Lewis, Emma M. Bonniwell, Janelle K. Lanham, Abdi Ghaffari, Hooshmand Sheshbaradaran, Andrew B. Cao, Maggie M. Calkins, Mario Alberto Bautista-Carro, Emily Arsenault, Andre Telfer, Fatimeh-Frouh Taghavi-Abkuh, Nicholas J. Malcolm, Fatema El Sayegh, Alfonso Abizaid, Yasmin Schmid, Kathleen Morton, Adam L. Halberstadt, Argel Aguilar-Valles, John D. McCorvy   +18 more
doaj   +1 more source

Assessment of Humoral Immune Response in Pre- and Post-Vaccinated Cattle Against Lumpy Skin Disease

Veterinary Medicine: Research and Reports, 2023
Nebyou Moje,1 Fufa Dawo Bari,1 Beksisa Urge,2 Ejigayehu Demissie2 1College of Veterinary Medicine and Agriculture, Addis Ababa University, Bishoftu, Ethiopia; 2Holeta and Debre Zeit Agricultural Research Centers, EIAR, Oromia, EthiopiaCorrespondence ...
Moje N, Bari FD, Urge B, Demissie E
doaj  

Identification and characterisation of lumpy skin disease virus recently isolated from Giza, Egypt (2018)

Bulgarian Journal of Veterinary Medicine, 2023
Lumpy skin disease (LSD) is a viral disease, geographically distributed in Africa and now, vigorously spread in the Near East and also in Europe and Asia. It has a significant economic impact on cattle industry in Africa.
C. A. Mikhael, H. G. Abd El Aziz , A. M. Ali   +2 more
doaj   +1 more source

Seroprevalence of Lumpy skin disease and associated risk factors in cattle in Kilolo District, Iringa Tanzania [PDF]

Journal of Applied Veterinary Sciences
Lumpy skin disease (LSD) is an infectious disease of cattle caused by lumpy skin disease virus (LSDV), which is a member of the Poxviridae family and genus Capripoxvirus.
Leonitha Leopord, Augustino Chengula, Esron Karimuribo   +2 more
doaj   +1 more source

Les racines psychédéliques des environnements de réalités virtuelles : Do it yourself theology versus do it yourself technology?

Interfaces Numériques, 2017
Cet article propose de réactiver la filiation qui relie les environnements de réalités virtuelles aux expériences hallucinogènes des années 1960 et remettre ainsi au centre de nos préoccupations la notion d’expansion de la conscience pour éclairer d’un ...
Franck Renucci, Hervé Zénouda
doaj   +1 more source

Impacts and Burden of Niemann pick Type-C: a patient and caregiver perspective

Orphanet Journal of Rare Diseases, 2021
Background Niemann-Pick disease type C (NPC) is a debilitating condition that impacts patients’ and caregivers’ quality of life (QOL) and reduces the patient’s life expectancy.
Eugen Mengel, Marc C. Patterson, Michael Chladek, Christina Guldberg, Christine í Dali, Tara Symonds, Lucy Lloyd-Price, Toni Mathieson, Joslyn Crowe, Claire Burbridge   +9 more
doaj   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

A positioning recognition method for SF6 pressure pointer meter

Diance yu yibiao
For SF6 pressure pointer meter with complex dial, internal mechanical components and short pointer, there is still a lack of a method of meter location identification with low computational cost and robustness and accuracy, which is suitable for poor ...
ZHAO Lina, ZHAO Lijuan, NING Zida, ZANG Yulai, XU Zhiniu   +4 more
doaj   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source