Results 41 to 50 of about 96,524 (256)

A Central Somatic Transmission Mediates Proprioceptive Facilitation of Muscle Pain

Advanced Science, EarlyView.
Zhang et al. uncover a novel central mechanism for persistent muscle pain, in which TRPA1 sensitization in MeV proprioceptive neurons enhances somatic secretion. This, in turn, disinhibits descending pain control from neighboring noradrenergic locus coeruleus neurons via local GABAergic circuits, thereby promoting inflammatory muscle pain.
Xiaoyu Zhang, Jiale Yang, Xi Wu, Jie Li, Fujian Lu, Yiman Li, Xingyu Du, Rong Huang, Jamila Asgar, Jing Wang, Ke Ren, Feipeng Zhu, Changhe Wang, Yehua Gan, Feng Wei, Zhuan Zhou   +15 more
wiley   +1 more source

Lumpy skin disease: A growing threat to the global livestock industry

Open Veterinary Journal
Lumpy Skin Disease (LSD) is an infectious disease in cattle caused by the Lumpy Skin Disease Virus (LSDV) from the Poxviridae family. Historically, LSD was first documented in Northern Rhodesia (now Zambia) in 1929 as a symptom of bug bite poisoning or ...
Nanik Hidayatik, Aswin Rafif Khairullah, M. Gandul Atik Yuliani, Eka Pramyrtha Hestianah, Arindita Niatazya Novianti, Ratna Damayanti, Mirza Atikah Madarina Hisyam, Ikechukwu Benjamin Moses, Riza Zainuddin Ahmad, Bantari Wisynu Kusuma Wardhani, Syahputra Wibowo, Dea Anita Ariani Kurniasih   +11 more
doaj   +1 more source

Paternal Circadian Disruption Impairs Offspring Cognition via Sperm microRNAs

Advanced Science, EarlyView.
Paternal circadian disruption remodels the sperm small RNA payload, elevating miR‐92a‐3p/miR‐25‐3p levels and perturbing early embryonic gene regulatory programs. Microinjection experiments and single‐embryo transcriptomics reveal sex‐specific developmental vulnerabilities, ultimately impairing offspring hippocampal synaptic plasticity and cognition ...
Kexin Zou, Sisi Luo, Binliang Tang, Zhiqiang Liu, Yuchuan Zhou, Yicong Meng, Zhengmu Wu, Zheng Sun, Weihui Shi, Jianzhong Sheng, Chuanjin Yu, Zhenhua Li, Siyi Wei, Mo Zhang, Yujie Luo, Jing Yan, Xueyun Qin, Jiahang Mo, Chengliang Zhou, Jinsong Li, Hefeng Huang, Yifu Ding, Guolian Ding   +22 more
wiley   +1 more source

Anesthesia and Drug Addicted Patients

Bagcilar Medical Bulletin
In recent years, drug use has been increasing worldwide and in our country. This article aimed to raise awareness about the difficulties that clinicians may encounter in patients with substance addiction during anesthesia and the management of these ...
Sibel Buluç Bulgen, Gözde Altun, Ayla Esin, Yasemin Özşahin, Kerem Erkalp, Ziya Salihoğlu   +5 more
doaj   +1 more source

Zinc Exposure Causes Disulfidptosis to Induce Miscarriage by Up‐Regulating GATA1/METTL1/SLC7A11 Axis

Advanced Science, EarlyView.
Zn exposure up‐regulates GATA1, promoting GATA1‐mediated METTL1 and SLC7A11 transcription. It also enhances METTL1‐mediated m7G modification on SLC7A11 mRNA, increasing SLC7A11 mRNA stability. Ultimately, Zn exposure up‐regulates SLC7A11 at both transcriptional and post‐transcriptional levels, causing disulfidptosis. Knockdown of murine Slc7a11, Gata1,
Wenxin Huang, Yi Sun, Yanxin Wang, Haijun Yan, Xiaoping Yue, Weidong Wu, Xueyu Chen, Jinfang Zhang, Yanbing Lin, Qiong Lei, Nan Ji, Shuaishuai Xing, Liqin Zeng, Qingzheng Kang, Depeng Zhao, Geng Guo, Huidong Zhang   +16 more
wiley   +1 more source

Dynamic Skyline Computation with LSD Trees

Analytics, 2023
Given a set of high-dimensional feature vectors S⊂Rn, the skyline or Pareto problem is to report the subset of vectors in S that are not dominated by any vector of S.
Dominik Köppl
doaj   +1 more source

A Brain‐Wide Atlas of Astrocytic Oxytocin Receptors Reveals a Glial Basis for Nucleus Accumbens Modulation of Affiliative Behavior

Advanced Science, EarlyView.
The cellular actors of oxytocin signaling are under intense scrutiny. A brain‐wide anatomical and functional analysis in mice and rats reveals widespread expression of oxytocin receptors in astrocytes. These receptors are functionally active and, in the nucleus accumbens, selectively regulate male social affiliation.
Clémence Denis, Stefan Stojilkovic, Kai‐Yi Wang, Cristina Márquez, Annabel C. Kleinwächter, Angel Baudon, Yuval Podpecan, Aurélia Ces, Mélanie Kremer, Isabelle Arnoux, Nathalie Rouach, Jemima Helen, Sophie Trender, Andreas Wallkum, Selina Wunsch, Franziska Schommer, Moritz C. Wimmer, Tim Schubert, Felix Franke, Jabir Aliyu Muhammad, Eva M. Eisemann, Ingrid Camila Possa‐Paranhos, Cassandra Baumann, Pierre‐Alexis Derrien, Quirin Krabichler, Cosmo Garcia, Henning Fröhlich, Matthew K. Kirchner, Valery Grinevich, Pascal Darbon, Javier E. Stern, Ferdinand Althammer, Alexandre Charlet   +32 more
wiley   +1 more source

Oral Motion‐Powered Smart Dental Implant Abutment for In Situ Antibacterial and Cell Adhesion Through Piezoelectric Effect

Advanced Science, EarlyView.
We proposed a method based on the piezoelectric effect and fabricated an implant abutment on the basis of piezoelectric ceramic. Under physiological occlusal pressure, the oral motion‐powered smart dental implant abutments interacted with water and oxygen, promoting the formation of reactive oxygen species and achieving a synergistic and highly ...
Xiyu Shi, Xiaoyu Han, Yanhui Lu, Yuan Chai, Baiyan Xiao, Shuo Liu, Boon Chin Heng, Tingting Wu, Tingjun Li, Qiaomei Ren, Ting Song, Le Chen, Dong Han, Yaru Guo, Xuliang Deng, Xuehui Zhang   +15 more
wiley   +1 more source

Kesesuaian Lahan Sawah Dilindungi (LSD) Terhadap Kebijakan Rencana Tata Ruang di Kabupaten Gianyar

Jurnal Ilmiah Telsinas
Pertumbuhan penduduk berimplikasi pada kebutuhan pangan. Pertumbuhan penduduk seharusnya diiringi dengan pertumbuhan ketersediaan pangan. Namun ketersediaan lahan untuk memenuhi kebutuhan manusia bersifat tetap, hal ini menyebabkan ketersediaan pangan ...
I Made Satya Graha, Inayatul Fikriyah
doaj   +1 more source

Influence of the Preparation Method on Some Characteristics of Alginate/Chitosan/Lovastatin Composites

Advances in Polymer Technology, 2020
This study investigates the effects of direct and indirect dispersion methods for lovastatin solid dispersion (LSD) in alginate (AG)/chitosan (CS) composites on the characteristics and properties of the AG/CS/LSD composites.
Duc-Thuan Nghiem, Thuy-Chinh Nguyen, Minh-Thanh Do, Thi-Huyen Nguyen, Dai Lam Tran, Tran-Dung Hoang, Van-Quan Le, Quoc-Trung Vu, Duy-Trinh Nguyen, Hoang Thai   +9 more
doaj   +1 more source