Results 51 to 60 of about 292,965 (296)

RETREG1‐Mediated Reticulophagy is Essential for Dendritic Cell Maturation and Function in Sepsis

open access: yesAdvanced Science, EarlyView.
Reticulophagy regulator 1 (RETREG1) maintains dendritic cell (DC) maturation and function in early sepsis. Mechanistically, activating transcription factor 6 (ATF6) acts as a direct transcription factor regulating RETREG1 expression in response to sepsis‐induced endoplasmic reticulum (ER) stress.
Ren‐Qi Yao   +28 more
wiley   +1 more source

Alumni DSA and teachers

open access: yesINFAD, 2018
As teacher with many years of experience and with the inclination to professional upgrading, a very irrevocable moment for the social function of a teacher , relating to the specific learing disability (LSD) not only the problems are linked to the ...
Maria Forte Bice
doaj   +1 more source

Power distribution investigation of a hexagonal diffused cellular indoor visible light communications system [PDF]

open access: yes, 2011
This paper presents a three dimensions (3D) model of optical power distribution in a diffused cellular indoor visible light communication (VLC) system.
Ghassemlooy, Zabih   +3 more
core  

Simulations of a Magnetic Fluctuation Driven Large Scale Dynamo and Comparison with a Two-scale Model

open access: yes, 2012
Models of large scale (magnetohydrodynamic) dynamos (LSD) which couple large scale field growth to total magnetic helicity evolution best predict the saturation of LSDs seen in simulations.
Alexakis   +23 more
core   +1 more source

Alterations of consciousness and mystical-type experiences after acute LSD in humans [PDF]

open access: yes, 2016
Lysergic acid diethylamide (LSD) is used recreationally and in clinical research. Acute mystical-type experiences that are acutely induced by hallucinogens are thought to contribute to their potential therapeutic effects.
Dolder, Patrick C.   +2 more
core   +2 more sources

GATA4‐Driven Transcription of HtrA1 Promotes Cellular Senescence in Ménière's Disease and Age‐Related Audio‐Vestibular Dysfunction

open access: yesAdvanced Science, EarlyView.
This study identifies the HDAC6/GATA4/HtrA1 axis as a critical driver of cellular senescence in the inner ear. GATA4 nuclear translocation, facilitated by HDAC6 downregulation, transcriptionally activates HtrA1, promoting hair cell senescence, SASP, and audio‐vestibular dysfunction in models of Ménière's disease and age‐related audio‐vestibular ...
Na Zhang   +16 more
wiley   +1 more source

A Central Somatic Transmission Mediates Proprioceptive Facilitation of Muscle Pain

open access: yesAdvanced Science, EarlyView.
Zhang et al. uncover a novel central mechanism for persistent muscle pain, in which TRPA1 sensitization in MeV proprioceptive neurons enhances somatic secretion. This, in turn, disinhibits descending pain control from neighboring noradrenergic locus coeruleus neurons via local GABAergic circuits, thereby promoting inflammatory muscle pain.
Xiaoyu Zhang   +15 more
wiley   +1 more source

Lumpy skin disease: A growing threat to the global livestock industry

open access: yesOpen Veterinary Journal
Lumpy Skin Disease (LSD) is an infectious disease in cattle caused by the Lumpy Skin Disease Virus (LSDV) from the Poxviridae family. Historically, LSD was first documented in Northern Rhodesia (now Zambia) in 1929 as a symptom of bug bite poisoning or ...
Nanik Hidayatik   +11 more
doaj   +1 more source

Magnetic fluctuations in 2D metals close to the Stoner instability

open access: yes, 2000
We consider the effect of potential disorder on magnetic properties of a two-dimensional metallic system (with conductance $g\gg 1$) when interaction in the triplet channel is so strong that the system is close to the threshold of the Stoner instability.
A. I. Larkin   +24 more
core   +1 more source

Paternal Circadian Disruption Impairs Offspring Cognition via Sperm microRNAs

open access: yesAdvanced Science, EarlyView.
Paternal circadian disruption remodels the sperm small RNA payload, elevating miR‐92a‐3p/miR‐25‐3p levels and perturbing early embryonic gene regulatory programs. Microinjection experiments and single‐embryo transcriptomics reveal sex‐specific developmental vulnerabilities, ultimately impairing offspring hippocampal synaptic plasticity and cognition ...
Kexin Zou   +22 more
wiley   +1 more source

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