Results 141 to 150 of about 24,350 (247)

Supplementary Fig. 1 from Disruption of the MYC Superenhancer Complex by Dual Targeting of FLT3 and LSD1 in Acute Myeloid Leukemia

open access: gold, 2023
William M. Yashar   +14 more
openalex   +1 more source

TERRA-LSD1 phase separation promotes R-loop formation for telomere maintenance in ALT cancer cells

open access: yesNature Communications
The telomere repeat-containing RNA (TERRA) forms R-loops to promote homology-directed DNA synthesis in the alternative lengthening of telomere (ALT) pathway.
Meng Xu   +15 more
doaj   +1 more source

FLI-06 suppresses proliferation, induces apoptosis and cell cycle arrest by targeting LSD1 and Notch pathway in esophageal squamous cell carcinoma cells

open access: hybrid, 2018
Zhaoming Lu   +8 more
openalex   +1 more source

Mechanisms of LSD1 regulation

open access: yes
The precise spatiotemporal regulation of gene expression is essential for all aspects of cellular function. Dysregulation of gene transcription can lead to serious pathologies, including severe malignancies and ultimately cell death. Consequently, complex regulatory mechanisms are essential to maintain and adapt gene expression in response to internal ...
openaire   +2 more sources

Region-specific alteration of histone modification by LSD1 inhibitor conjugated with pyrrole-imidazole polyamide [PDF]

open access: diamond, 2018
Kokiladevi Alagarswamy   +14 more
openalex   +1 more source

Supplementary Fig. 9 from Disruption of the MYC Superenhancer Complex by Dual Targeting of FLT3 and LSD1 in Acute Myeloid Leukemia

open access: gold, 2023
William M. Yashar   +14 more
openalex   +1 more source

Scaffolding LSD1 Inhibitors Impair NK Cell Metabolism and Cytotoxic Function Through Depletion of Glutathione [PDF]

open access: gold, 2020
Cavan P. Bailey   +4 more
openalex   +1 more source

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