Results 121 to 130 of about 12,312 (182)

Regulation of androgen receptor expression by enhancer elements in prostate cancer. [PDF]

Exp Mol Med
Khadka S, Jeon HY, Hussain A, Qi J.
europepmc   +1 more source

LSD1 inhibition sensitizes anti-PD1 blockade immunotherapy by inhibiting the long-range attack of tumor-derived extracellular vesicles. [PDF]

Acta Pharm Sin B
Zhao Y, Zhang D, Meng L, Shan S, Zhang C, Deng Z, Han C, Kong L.   +7 more
europepmc   +1 more source

Context-dependent crosstalk between DNA methylation and histone modifications shapes durable CRISPR/dCas9-based epigenetic editing

Josipović G, Foglar N, Vujić A, Lukšić F, Wang Q, Bočkor VV, Klasić M, Habazin S, Mijakovac A, Vojta A, Zoldoš V.   +10 more
europepmc   +1 more source

Lysine-specific histone demethylase complex restricts Epstein-Barr virus lytic reactivation. [PDF]

Nat Microbiol
Liao Y, Yan J, Kong IY, Li Z, Ding W, Clark S, Maestri D, Yoshida T, Giulino-Roth L, Gewurz BE.   +9 more
europepmc   +1 more source

Multifaceted regulatory role of proline‑ and glutamine-rich splicing factor in tumors (Review). [PDF]

Mol Med Rep
Zhang S, Li Z, Fu L.
europepmc   +1 more source

Histone modification cross-talk: analytical tools and molecular mechanisms. [PDF]

Biochem J
Jiang J, DuBois-Coyne S, Nam E, Whedon SD, Lee K, Cole PA.   +5 more
europepmc   +1 more source

Targeting epigenetic methylation: emerging diagnosis and therapeutic strategies in cancer. [PDF]

Exp Hematol Oncol
Zhu Y, Liu K, Zhu H.
europepmc   +1 more source

CoREST complex inhibition alters RNA splicing to promote neoantigen expression and enhance tumor immunity. [PDF]

JCI Insight
Fisher RJ, Park K, Lee K, Pinjusic K, Vanasse A, Ennis CS, Farokh P, Ficaro SB, Marto JA, Jiang H, Nam E, Stransky S, Duke-Cohan J, Akinci MA, Geethadevi A, Raabe E, Fiszbein A, Demehri S, Sidoli S, Hicks CW, Keskin DB, Wu CJ, Cole PA, Alani RM.   +23 more
europepmc   +1 more source

Drug Repurposing for AML: Structure-Based Virtual Screening and Molecular Simulations of FDA-Approved Compounds with Polypharmacological Potential. [PDF]

Biomedicines
Abdelsayed M, Boulaamane Y.
europepmc   +1 more source

Discovery of LD-110 as an Effective LSD1 PROTAC Degrader for the Treatment of Esophagus Squamous Cancer. [PDF]

J Med Chem
Zhuo J, Zhai D, Liu L, Yin Y, Zhong C, Chen Q, You X, Chen L, Yu Q, Xiong X, Sun Y, Han X.   +11 more
europepmc   +1 more source